Challenges in exosome isolation and analysis in health and disease

N Ludwig, TL Whiteside, TE Reichert - International journal of molecular …, 2019 - mdpi.com
A growing body of evidence emphasizes the important role exosomes in different
physiological and pathological conditions. Exosomes, virus-size extracellular vesicles (EVs) …

Boosting extracellular vesicle secretion

L Debbi, S Guo, D Safina, S Levenberg - Biotechnology advances, 2022 - Elsevier
In recent years, extracellular vesicles (EVs), specifically exosomes, have emerged as a
promising strategy for treating a wide spectrum of pathologies, such as cancer and COVID …

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …

C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …

Determinants of maternal insulin resistance during pregnancy: an updated overview

U Kampmann, S Knorr, J Fuglsang… - Journal of diabetes …, 2019 - Wiley Online Library
Insulin resistance changes over time during pregnancy, and in the last half of the pregnancy,
insulin resistance increases considerably and can become severe, especially in women with …

Progress in microfluidics‐based exosome separation and detection technologies for diagnostic applications

S Lin, Z Yu, D Chen, Z Wang, J Miao, Q Li, D Zhang… - Small, 2020 - Wiley Online Library
Exosomes are secreted by most cell types and circulate in body fluids. Recent studies have
revealed that exosomes play a significant role in intercellular communication and are closely …

Biological functions and current advances in isolation and detection strategies for exosome nanovesicles

K Boriachek, MN Islam, A Möller, C Salomon… - Small, 2018 - Wiley Online Library
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …

Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement

C Salomon, S Das, U Erdbrügger, R Kalluri… - Endocrine …, 2022 - academic.oup.com
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

Placental exosomes as early biomarker of preeclampsia: potential role of exosomal microRNAs across gestation

C Salomon, D Guanzon… - The Journal of …, 2017 - academic.oup.com
Context There is a need to develop strategies for early prediction of patients who will
develop preeclampsia (PE) to establish preventive strategies to reduce the prevalence and …

Gestational diabetes mellitus is associated with changes in the concentration and bioactivity of placenta-derived exosomes in maternal circulation across gestation

C Salomon, K Scholz-Romero, S Sarker, E Sweeney… - Diabetes, 2016 - Am Diabetes Assoc
Although there is significant interest in elucidating the role of placenta-derived exosomes
(PdEs) during pregnancy, the exosomal profile in pregnancies complicated by gestational …

Biological features of extracellular vesicles and challenges

Y Zeng, Y Qiu, W Jiang, J Shen, X Yao, X He… - Frontiers in Cell and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are vesicles with a lipid bilayer membrane on the outside, which
are widely found in various body fluids and contain biological macromolecules such as …