Inhibition of tumor necrosis factor (TNF)-α action has recently been shown to reverse insulin
resistance dramatically and to improve glycemic control in obese rodents. This double-blind …

Serum GH concentrations are increased in fasted or malnourished human subjects. We
investigated the dynamic mechanisms underlying this phenomenon in nine normal men by …

Purpose Pyruvate uptake is higher in human embryos developing to the blastocyst stage
than those arresting at cleavage stages. To investigate whether pyruvate uptake provides an …

AIM To investigate the relation between common acid-base parameters and blood lactate
concentrations and their prognostic importance in sick, ventilated neonates. METHODS Two …

Decreased insulin sensitivity is associated with diabetes mellitus, ischemic heart disease,
and hypertension, both independently and in association as what is called the metabolic …

To determine if insulin-like growth factor I (IGF-I) inhibits pulsatile growth hormone (GH)
secretion in man, recombinant human IGF-I (rhIGF-I) was infused for 6 h at 10 micrograms …

A stepped intravenous metformin infusion was used in conjunction with the hyperglycaemic
clamp technique to study the dose‐response relationship of plasma metformin concentration …

Stimulation of lipolysis and the induction of resistance to insulin's actions on glucose
metabolism are well-recognized effects of growth hormone (GH). To evaluate whether these …

Previous studies have suggested that glucagon-like peptide-1 (GLP-1)(7–36 amide) may
have the direct effect of increasing insulin sensitivity in healthy man. To evaluate this …

The ability of growth hormone (GH) to stimulate lipolysis and cause insulin resistance in
skeletal muscle may be causally linked, but the mechanisms remain obscure. We …