Oxidative stress and antioxidant system in periodontitis

Y Wang, O Andrukhov, X Rausch-Fan - Frontiers in physiology, 2017 - frontiersin.org
Periodontitis is a common inflammatory disease, which is initiated by bacterial infection and
subsequently progressed by aberrant host response. It can result in the destruction of teeth …

Oxidative stress‐related biomarkers in saliva and gingival crevicular fluid associated with chronic periodontitis: A systematic review and meta‐analysis

M Chen, W Cai, S Zhao, L Shi, Y Chen… - Journal of clinical …, 2019 - Wiley Online Library
Aim Oxidative stress (OS) biomarkers have been detected in saliva and gingival crevicular
fluid (GCF) during chronic periodontitis (CP) progression; however, the relationship between …

The role of reactive oxygen species and autophagy in periodontitis and their potential linkage

C Liu, L Mo, Y Niu, X Li, X Zhou, X Xu - Frontiers in physiology, 2017 - frontiersin.org
Periodontitis is a chronic inflammatory disease that causes damage to periodontal tissues,
which include the gingiva, periodontal ligament, and alveolar bone. The major cause of …

Oxidative stress and antioxidants in the diagnosis and therapy of periodontitis

L Tóthová, P Celec - Frontiers in physiology, 2017 - frontiersin.org
Oxidative stress has been implicated in the pathogenesis of numerous diseases. However,
large interventional studies with antioxidants failed to show benefits in the prevention or …

Total oxidant and antioxidant capacity of gingival crevicular fluid and saliva in patients with periodontitis: review and clinical study

J Toczewska, M Maciejczyk, T Konopka, A Zalewska - Antioxidants, 2020 - mdpi.com
Periodontitis is inextricably linked to oxidative-reductive (redox) imbalance. However, little is
still known about the resultant ability to scavenge oxygen free radicals in saliva and gingival …

The emerging role of salivary oxidative stress biomarkers as prognostic markers of periodontitis: new insights for a personalized approach in dentistry

G Viglianisi, GM Tartaglia, S Santonocito… - Journal of personalized …, 2023 - mdpi.com
Periodontitis is a multifactorial and infective oral disease that leads to the destruction of
periodontal tissues and tooth loss. Although the treatment of periodontitis has improved …

Evaluation of salivary and serum antioxidant and oxidative stress statuses in patients with chronic periodontitis: a case-control study

F Ahmadi-Motamayel, MT Goodarzi, Z Jamshidi… - Frontiers in …, 2017 - frontiersin.org
Aim: Local bacteria stimulate polymorphonuclear neutrophils to release reactive oxygen
species in periodontitis. Increased levels of oxidative stress play a significant role in the …

Porphyromonas gingivalis Infection Promoted the Proliferation of Oral Squamous Cell Carcinoma Cells through the miR-21/PDCD4/AP-1 Negative Signaling Pathway

C Chang, H Wang, J Liu, C Pan, D Zhang… - ACS Infectious …, 2019 - ACS Publications
Recent epidemiological studies have revealed that Porphyromonas gingivalis, a major
pathogen in periodontal disease, is associated with the development of oral squamous cell …

Oxidative stress in chronic periodontitis patients with type II diabetes mellitus

RR Vincent, D Appukuttan, DJ Victor… - European journal of …, 2018 - thieme-connect.com
Objective: Oxidative stress (OS) refers to the disequilibrium between free radicals and
antioxidant defense mechanisms and is significantly implicated in the pathogenesis of …

Effect of locally delivered melatonin as an adjunct to nonsurgical therapy on GCF antioxidant capacity and MMP‐9 in stage II periodontitis patients: a randomized …

E Ahmed, OG Shaker, N Yussif… - International journal of …, 2021 - Wiley Online Library
Objectives. Periodontitis is characterized by inflammatory destruction of periodontal tissue,
loss of attachment, and bone resorption. The increase in reactive oxygen species (ROS) is …