Hydrogen peroxide (H2O2) is continuously formed by the autoxidation of redox enzymes in
aerobic cells, and it also enters from the environment, where it can be generated both by …

Excessive hydrogen peroxide is harmful for almost all cell components, so its rapid and
efficient removal is of essential importance for aerobically living organisms. Conversely …

ENDscript 2 is a friendly Web server for extracting and rendering a comprehensive analysis
of primary to quaternary protein structure information in an automated way. This major …

Human catalase is an heme-containing peroxisomal enzyme that breaks down hydrogen
peroxide to water and oxygen; it is implicated in ethanol metabolism, inflammation …

This review gives an overview about the structural organisation of different evolutionary lines
of all enzymes capable of efficient dismutation of hydrogen peroxide. Major potential …

The roles of methionine residues in proteins have not been well defined, but a review of
available studies leads to the conclusion that methionine, like cysteine, functions as an …

Catalases from 16 different organisms including representatives from all three phylogenetic
clades were purified and characterized to provide a comparative picture of their respective …

Catalases are well studied enzymes that play critical roles in protecting cells against the
toxic effects of hydrogen peroxide. The ubiquity of the enzyme and the availability of …

NADPH is known to be tightly bound to mammalian catalase and to offset the ability of the
substrate of catalase (H 2 O 2) to convert the enzyme to an inactive state (compound II). In …

Catalases continue to present a challenge and are an object of interest to the biochemist
despite more than 100 years of study. More than 120 sequences, seven crystal structures …