Sex-specific proteomic changes induced by genetic deletion of fibroblast growth factor 14 (FGF14), a regulator of neuronal ion channels
Fibroblast growth factor 14 (FGF14) is a member of the intracellular FGFs, which is a group
of proteins involved in neuronal ion channel regulation and synaptic transmission. We …
of proteins involved in neuronal ion channel regulation and synaptic transmission. We …
Seeking Therapies for Spinocerebellar Ataxia: From Gene Silencing to Systems-Based Approaches
R Powers, H Paulson, S Srinivasan - Trials for Cerebellar Ataxias: From …, 2023 - Springer
Recent progress has led to nucleotide-based gene silencing strategies as a potential
therapy for spinocerebellar ataxia type 3 (SCA3) and other hereditary ataxias. But recent …
therapy for spinocerebellar ataxia type 3 (SCA3) and other hereditary ataxias. But recent …
Ion Channel Genes and Ataxia
M Padmanaban, CM Gomez - Trials for Cerebellar Ataxias: From Cellular …, 2023 - Springer
In this review we will discuss ataxic disorders attributed to mutations in ion channel genes.
Such disorders seem to preferentially effect cerebellar Purkinje cell function, but not …
Such disorders seem to preferentially effect cerebellar Purkinje cell function, but not …