Fluid homeostasis in vertebrates critically relies on the lymphatic system forming a
hierarchical network of lymphatic capillaries and collecting lymphatics, for the efficient …

The most common cause of death in the developed world is cardiovascular disease. For
decades, this has provided a powerful motivation to study the effects of mechanical forces on …

Abstract Using an Atomic Force Microscope (AFM) with a 5.3 μm diameter spherical probe,
we determined mechanical properties of individual human mammary epithelial cells. The …

Biological tissues experience various stretch gradients which act as mechanical signaling
from the extracellular environment to cells. These mechanical stimuli are sensed by cells …

The strain-induced reorientation response of cyclically stretched cells has been well
characterized in uniform strain fields. In the present study, we comprehensively analyse the …

The lymphatic vasculature is responsible for fluid homeostasis, transport of immune cells,
inflammatory molecules, and dietary lipids. It is composed of a network of lymphatic …

Cells within connective tissues are routinely subjected to a wide range of non-uniform
mechanical loads that regulate many cell behaviors. In the present study, the relationship …

Abstract 3D printing was used to develop an open access device capable of simultaneous
electrical and mechanical stimulation of human induced pluripotent stem cells in 6-well …

Substrate deformation affects the behaviour of many cell types, including bone, skeletal
muscle and endothelial cells. Nowadays, in vitro tests are widely employed to study the …

Although there have been a number of studies regarding tenogenic differentiation of human
bone marrow mesenchymal stem cells (hBMSCs) using uniaxial cyclic stretching stimulation …