Adenosine is a neuromodulator with several functions in the central nervous system (CNS),
such as inhibition of neuronal activity in many signaling pathways. Most of the sedating …

Pannexin 1 (Panx1) represents a class of vertebrate membrane channels, bearing
significant sequence homology with the invertebrate gap junction proteins, the innexins and …

A patient with epilepsy was shown to have neurobiological, psychological, cognitive, and
social issues as a result of recurring seizures, which is regarded as a chronic brain disease …

Purpose: To investigate the effects of low frequency stimulation (LFS) of a fiber tract for the
suppression of spontaneous seizures in a rat model of human temporal lobe epilepsy …

Unlike an electrical circuit, the hardware of the brain is susceptible to change. Repeated
electrical brain stimulation mimics epileptogenesis. After such “kindling” process, a …

Kindling results in abnormal synaptic potentiation and significant impairment in learning and
memory. Electromagnetic field (EMF) effects on learning and memory in kindled animals and …

Kindled seizures can impair learning and memory. In the present study the effect of low-
frequency electrical stimulation (LFS) on kindled seizure-induced impairment in spatial …

Despite the effectiveness of anterior thalamic nucleus (AN) deep brain stimulation (DBS) for
the treatment of epilepsy, mechanisms responsible for the antiepileptic effects of this therapy …

Deep brain stimulation (DBS) has been investigated for the treatment of epilepsy. In rodents,
an increase in the latency for the development of seizures and status epilepticus (SE) has …

Low frequency stimulation (LFS) may be considered as a new potential therapy for drug-
resistant epilepsy. However, the relation between LFS parameters and its anticonvulsant …