Artificial biocatalytic linear cascades for preparation of organic molecules

JH Schrittwieser, S Velikogne, M Hall… - Chemical …, 2018 - ACS Publications
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Recent advances in whole cell biocatalysis techniques bridging from investigative to industrial scale

J Wachtmeister, D Rother - Current opinion in biotechnology, 2016 - Elsevier
Highlights•The use of whole cell biocatalysts is appealing due to their inexpensive
production.•Applications in unconventional media allow high substrate and product …

Multienzyme Cascade Reactions Status and Recent Advances

JM Sperl, V Sieber - Acs Catalysis, 2018 - ACS Publications
Cascade reactions catalyzed by multienzymatic systems have strongly moved into the focus
of researchers in the field of biocatalysis because of their unique potential for the …

Constructing biocatalytic cascades: in vitro and in vivo approaches to de novo multi-enzyme pathways

SP France, LJ Hepworth, NJ Turner, SL Flitsch - Acs Catalysis, 2017 - ACS Publications
The combination of sequential biocatalytic reactions, via non-natural synthetic cascades, is a
rapidly developing field and leads to the generation of complex valuable chemicals from …

Cascade catalysis–strategies and challenges en route to preparative synthetic biology

J Muschiol, C Peters, N Oberleitner… - Chemical …, 2015 - pubs.rsc.org
Nature's smartness and efficient assembling cascade type reactions inspired biologists and
chemists all around the world. Tremendous effort has been directed towards the …

Recent developments of cascade reactions involving ω-transaminases

RC Simon, N Richter, E Busto, W Kroutil - ACS catalysis, 2014 - ACS Publications
Enzymatic cascade reactions experience tremendous attention by cutting short conventional
step-by-step synthesis in a highly efficient and elegant fashion. Focusing on ω …

Alcohol dehydrogenases as catalysts in organic synthesis

AS de Miranda, CDF Milagre, F Hollmann - Frontiers in Catalysis, 2022 - frontiersin.org
Alcohol dehydrogenases (ADHs) have become important catalysts for stereoselective
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …

Multienzymatic cascades and nanomaterial scaffolding—a potential way forward for the efficient biosynthesis of novel chemical products

SL Hooe, AD Smith, SN Dean, JC Breger… - Advanced …, 2024 - Wiley Online Library
Synthetic biology is touted as the next industrial revolution as it promises access to greener
biocatalytic syntheses to replace many industrial organic chemistries. Here, it is shown to …

Whole‐cell cascade biotransformations for one‐pot multistep organic synthesis

S Wu, Z Li - ChemCatChem, 2018 - Wiley Online Library
Performing one‐pot multi‐catalysis reactions is a revolutionary tool for multistep synthesis,
representing a fast‐developing theme in catalysis field. To develop cascade reactions …

Baeyer-Villiger oxidations: biotechnological approach

M Bučko, P Gemeiner, A Schenkmayerová… - Applied microbiology …, 2016 - Springer
Abstract Baeyer-Villiger monooxygenases (BVMOs) are a very well-known and intensively
studied class of flavin-dependent enzymes. Their substrate promiscuity, high chemo-, regio …