Screening and prevention of colorectal cancer

P Kanth, JM Inadomi - Bmj, 2021 - bmj.com
Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

An update on the epidemiology, molecular characterization, diagnosis, and screening strategies for early-onset colorectal cancer

AN Burnett-Hartman, JK Lee, J Demb, S Gupta - Gastroenterology, 2021 - Elsevier
Rising trends in the incidence and mortality of early-onset colorectal cancer (CRC) in those
who are younger than 50 years have been well established. These trends have spurred …

[HTML][HTML] Epidemiology and biology of early onset colorectal cancer

A Venugopal, JM Carethers - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality in men or
women in the United States. Average-risk screening that begins at age 50 years has …

Red-flag signs and symptoms for earlier diagnosis of early-onset colorectal cancer

CDL Fritz, EE Otegbeye, X Zong, J Demb… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Prompt detection of colorectal cancer (CRC) among individuals younger than
age 50 years (early-onset CRC) is a clinical priority because of its alarming rise. Methods …

Early-onset colorectal cancer: current insights

F Ullah, AB Pillai, N Omar, D Dima, S Harichand - Cancers, 2023 - mdpi.com
Simple Summary Early-onset colorectal cancer is increasing in incidence in the United
States, and it is expected to more than double in the next 10 years. There are many risk …

Early-onset cancers in adults: A review of epidemiology, supportive care needs and future research priorities

AC Hamilton, DW Donnelly, D Fitzpatrick, HG Coleman - Cancers, 2022 - mdpi.com
Simple Summary Early-onset cancers, defined as cancers in adults aged 18 to 49 years, are
increasing in a number of cancer sites in developed countries. Cancers commonly seen in …

Early-onset colorectal cancer

V Nfonsam, E Wusterbarth, A Gong, P Vij - Surgical Oncology Clinics of …, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer in the world and is a leading
cause of morbidity and mortality. 1 In the United States, it is associated with the third highest …

SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

AJ Njouendou, T Szarvas, AAZ Tiofack, RN Kenfack… - Molecular Cancer, 2023 - Springer
Background Inflammation is undoubtedly a hallmark of cancer development. Its
maintenance within tumors and the consequences on disease aggressiveness are …

AGA clinical practice update on young adult–onset colorectal cancer diagnosis and management: expert review

LA Boardman, E Vilar, YN You, J Samadder - Clinical Gastroenterology …, 2020 - Elsevier
Description The objectives of this expert review are:(1) to prepare clinicians to recognize the
presentation and evidence-based risk factors for young adult–onset colorectal cancer …

[HTML][HTML] A distinct innate immune signature of early onset colorectal cancer

IH Gardner, R Siddharthan, K Watson, E Dewey… - …, 2021 - journals.aai.org
Despite a decrease in the prevalence of colorectal cancer (CRC) over the last 40 y, the
prevalence of CRC in people under 50 y old is increasing around the globe. Early onset (≤ …