Characterization of endogenous G-CSF and the inverse correlation to chemotherapy-induced neutropenia in patients with breast cancer using population modeling
AL Quartino, MO Karlsson, H Lindman… - Pharmaceutical …, 2014 - Springer
Purpose Neutropenia is a severe adverse-event of chemotherapeutics. Neutrophils (ANC)
are mainly regulated by granulocyte colony stimulating factor (G-CSF). The aim was to …
are mainly regulated by granulocyte colony stimulating factor (G-CSF). The aim was to …
Model-based approach to describe G-CSF effects in carboplatin-treated cancer patients
ML Pastor, CM Laffont, L Gladieff, A Schmitt… - Pharmaceutical …, 2013 - Springer
Purpose Granulocyte colony-stimulating factor (G-CSF) is often used in cancer patients
receiving cytotoxic drugs to prevent or reduce high grade neutropenia. We propose a …
receiving cytotoxic drugs to prevent or reduce high grade neutropenia. We propose a …
Modélisation par une approche de population de l'effet des facteurs de croissance granulocytaire lors de neutropénies chimio-induites
P Macaire - 2020 - theses.hal.science
Les travaux de cette thèse s' appuient sur les résultats d'une étude de cohorte ayant pour
objectif principal de définir le schéma optimal d'administration prophylactique des facteurs …
objectif principal de définir le schéma optimal d'administration prophylactique des facteurs …
Pharmacometric Models for Improved Prediction of Myelosuppression and Treatment Response in Oncology
AL Quartino - 2011 - diva-portal.org
Cancer is the second leading cause of death in the US and Europe (World Health
Organization) and even though there has been a profound improvement of the treatment of …
Organization) and even though there has been a profound improvement of the treatment of …
Comparison of the rapidity of onset of the therapeutic effect between nateglinide and mitiglinide by PK/PD analysis in rats
T Takanohashi, H Arisaka, K Ubukata… - European journal of …, 2012 - Springer
Nateglinide and mitiglinide are immediate short-acting insulinotropic agents. Both are
administered preprandially to control postprandial hyperglycemia. Glinide drugs are …
administered preprandially to control postprandial hyperglycemia. Glinide drugs are …
[PDF][PDF] Simultaneous modeling of endogenous G‑CSF and neutrophil dynamics following chemotherapy in breast cancer patients
Purpose: Neutropenia is a common and serious side-effect of chemotherapeutics. The main
regulating factor for neutrophils (ANC) is granulocyte colony stimulating factor (G-CSF) …
regulating factor for neutrophils (ANC) is granulocyte colony stimulating factor (G-CSF) …