The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR),
and thioredoxin, is a key antioxidant system in defense against oxidative stress through its …

A common need for microbial cells is the ability to respond to potentially toxic environmental
insults. Here we review the progress in understanding the response of the yeast …

Background Growing evidence suggests that oxidative stress forms a key component in the
etiopathogenesis of periodontitis. Studies have shown potential antioxidants responsible for …

The first suggestion that physical exercise results in free radical-mediated damage to tissues
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …

It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …

Convincing concepts of redox control of gene transcription have been worked out for
prokaryotes and lower eukaryotes, whereas the knowledge on complex mammalian systems …

'Reactive species'(RS) of various types are formed in vivo and many are powerful oxidizing
agents, capable of damaging DNA and other biomolecules. Increased formation of RS can …

Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

Background Lignin is the most abundant aromatic biopolymer in the biosphere and it
comprises up to 30% of plant biomass. Although lignin is the most recalcitrant component of …

S-Nitrosylation, the redox-based modification of Cys thiol side chains by nitric oxide, is a
common mechanism in signal transduction. Dysregulated S-nitrosylation contributes to a …