Strategies for generating diverse antibody repertoires using transgenic animals expressing human antibodies
WC Chen, CM Murawsky - Frontiers in immunology, 2018 - frontiersin.org
Therapeutic molecules derived from antibodies have become a dominant class of drugs
used to treat human disease. Increasingly, therapeutic antibodies are discovered using …
used to treat human disease. Increasingly, therapeutic antibodies are discovered using …
Probing morbillivirus antisera neutralization using functional chimerism between measles virus and canine distemper virus envelope glycoproteins
MA Muñoz-Alía, SJ Russell - Viruses, 2019 - mdpi.com
Measles virus (MeV) is monotypic. Live virus challenge provokes a broadly protective
humoral immune response that neutralizes all known measles genotypes. The two surface …
humoral immune response that neutralizes all known measles genotypes. The two surface …
Functionally convergent B cell receptor sequences in transgenic rats expressing a human B cell repertoire in response to tetanus toxoid and measles antigens
JP Bürckert, ARSX Dubois, WJ Faison… - Frontiers in …, 2017 - frontiersin.org
The identification and tracking of antigen-specific immunoglobulin (Ig) sequences within
total Ig repertoires is central to high-throughput sequencing (HTS) studies of infections or …
total Ig repertoires is central to high-throughput sequencing (HTS) studies of infections or …
[PDF][PDF] Characterization of Immunoglobulin Repertoires after Vaccination in OmniRatTM and Monoclonal CD5+ B Cell Expansion in A20BKOsCYLDBOE Mice using an …
JP Bürckert - 2019 - ubt.opus.hbz-nrw.de
Immunoglobulin (IG) molecules are the primary effectors of the humoral immune response.
In theory, IG can bind to every possible antigen through the large variety of immunoglobulin …
In theory, IG can bind to every possible antigen through the large variety of immunoglobulin …