Migrasomes, a new mode of intercellular communication

Y Jiang, X Liu, J Ye, Y Ma, J Mao, D Feng… - Cell Communication and …, 2023 - Springer
Migrasomes are newly discovered extracellular vesicles (EVs) that are formed in migrating
cells and mediate intercellular communication. However, their size, biological generation …

Migrasome: a new functional extracellular vesicle

X Zhang, L Yao, Y Meng, B Li, Y Yang, F Gao - Cell Death Discovery, 2023 - nature.com
Migrasome is a novel cellular organelle produced during cell migration, and its biogenesis
depends on the migration process. It is generated in a variety of cells such as immune cells …

Bioactive silica nanoparticles target autophagy, NF-κB, and MAPK pathways to inhibit osteoclastogenesis

J Arnst, Z Jing, C Cohen, SW Ha, M Viggeswarapu… - Biomaterials, 2023 - Elsevier
Spherical 50 nm silica-based nanoparticles (SiNPs) promote healthy bone homeostasis and
maintenance by supporting bone forming osteoblast lineage cells while simultaneously …

Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis

Y Zhao, J Ning, H Teng, Y Deng, M Sheldon… - Nature …, 2024 - nature.com
MALAT1, one of the few highly conserved nuclear long noncoding RNAs (lncRNAs), is
abundantly expressed in normal tissues. Previously, targeted inactivation and genetic …

Migrasomes: from biogenesis, release, uptake, rupture to homeostasis and diseases

Y Zhang, W Guo, M Bi, W Liu, L Zhou… - Oxidative Medicine …, 2022 - Wiley Online Library
Migrasomes are migration‐dependent membrane‐bound vesicular structures that contain
cellular contents and small vesicles. Migrasomes grow on the tips or intersections of the …

14-3-3ζ suppresses RANKL signaling by destabilizing TRAF6

R Ayyasamy, S Fan, P Czernik, B Lecka-Czernik… - Journal of Biological …, 2024 - jbc.org
Macrophages are essential regulators of inflammation and bone loss. Receptor activator of
nuclear factor-κβ ligand (RANKL), a pro-inflammatory cytokine, is responsible for …

[HTML][HTML] Migrasome, a novel organelle, differs from exosomes

X Tan, S He, F Wang, L Li, W Wang - Biochemistry and Biophysics Reports, 2023 - Elsevier
Migrasomes, a newly discovered organelle produced by migrating cells, are vesicles with
membranous structure that form on the tips and intersections of retraction fibers (RFs). These …

miR-146a Protects against Staphylococcus aureus-Induced Osteomyelitis by Regulating Inflammation and Osteogenesis

C Jiang, Y Lin, H Shan, W Xia, C Pan… - ACS infectious …, 2022 - ACS Publications
Osteomyelitis is a Staphylococcus aureus-caused bone infection. In this study, the effects of
miR-146a on osteomyelitis were evaluated. Using the osteoblast cell model and S. aureus …

Research progress of migrasomes: From genesis to formation, physiology to pathology

H Tang, Z Huang, M Wang, X Luan, Z Deng… - Frontiers in Cell and …, 2024 - frontiersin.org
Migrasomes are recently identified organelles that form at the ends or forks of retraction
fibers (RFs) behind migrating cells and are expelled from the cell through cell migration …

[HTML][HTML] “Three birds, one stone” strategy of NIR-responsive CO/H2S dual-gas Nanogenerator for efficient treatment of osteoporosis

G Yang, J Ye, J Wang, H Liu, Y Long, J Jiang, X Miao… - Materials Today Bio, 2024 - Elsevier
Osteoporosis (OP), the most prevalent bone degenerative disease, has become a significant
public health challenge globally. Current therapies primarily target inhibiting osteoclast …