[HTML][HTML] Cognitive dysfunction in schizophrenia: an expert group paper on the current state of the art

PD Harvey, M Bosia, R Cavallaro, OD Howes… - Schizophrenia Research …, 2022 - Elsevier
Cognitive impairment in schizophrenia represents one of the main obstacles to clinical and
functional recovery. This expert group paper brings together experts in schizophrenia …

22q11. 2 deletion syndrome

DM McDonald-McGinn, KE Sullivan, B Marino… - Nature reviews Disease …, 2015 - nature.com
Abstract 22q11. 2 deletion syndrome (22q11. 2DS) is the most common chromosomal
microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic …

How effective are cognitive behavior therapies for major depression and anxiety disorders? A meta‐analytic update of the evidence

P Cuijpers, IA Cristea, E Karyotaki… - World …, 2016 - Wiley Online Library
We report the current best estimate of the effects of cognitive behavior therapy (CBT) in the
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …

Using common genetic variation to examine phenotypic expression and risk prediction in 22q11. 2 deletion syndrome

RW Davies, AM Fiksinski, EJ Breetvelt, NM Williams… - Nature medicine, 2020 - nature.com
Abstract The 22q11. 2 deletion syndrome (22q11DS) is associated with a 20–25% risk of
schizophrenia. In a cohort of 962 individuals with 22q11DS, we examined the shared …

The CLDN5 gene at the blood-brain barrier in health and disease

Y Hashimoto, C Greene, A Munnich… - Fluids and Barriers of the …, 2023 - Springer
The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …

[HTML][HTML] Updated clinical practice recommendations for managing children with 22q11. 2 deletion syndrome

S Oskarsdottir, E Boot, TB Crowley, JCY Loo… - Genetics in …, 2023 - Elsevier
This review aimed to update the clinical practice guidelines for managing children and
adolescents with 22q11. 2 deletion syndrome (22q11. 2DS). The 22q11. 2 Society, the …

[HTML][HTML] Updated clinical practice recommendations for managing adults with 22q11. 2 deletion syndrome

E Boot, S Oskarsdottir, JCY Loo, TB Crowley… - Genetics in …, 2023 - Elsevier
This review aimed to update the clinical practice guidelines for managing adults with 22q11.
2 deletion syndrome (22q11. 2DS). The 22q11. 2 Society recruited expert clinicians …

The contribution of copy number variants to psychiatric symptoms and cognitive ability

J Mollon, L Almasy, S Jacquemont, DC Glahn - Molecular psychiatry, 2023 - nature.com
Copy number variants (CNVs) are deletions and duplications of DNA sequence. The most
frequently studied CNVs, which are described in this review, are recurrent CNVs that occur …

What is new with 22q? An update from the 22q and You Center at the Children's Hospital of Philadelphia

IM Campbell, SE Sheppard, TB Crowley… - American Journal of …, 2018 - Wiley Online Library
22q11. 2 deletion syndrome (22q11. 2DS) is a disorder caused by recurrent, chromosome‐
specific, low copy repeat (LCR)–mediated copy‐number losses of chromosome 22q11. The …

Molecular genetics of 22q11. 2 deletion syndrome

BE Morrow, DM McDonald‐McGinn… - American journal of …, 2018 - Wiley Online Library
The 22q11. 2 deletion syndrome (22q11. 2DS) is a congenital malformation and
neuropsychiatric disorder caused by meiotic chromosome rearrangements. One of the goals …