Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Long non-coding RNAs: new players in cell differentiation and development

A Fatica, I Bozzoni - Nature Reviews Genetics, 2014 - nature.com
Genomes of multicellular organisms are characterized by the pervasive expression of
different types of non-coding RNAs (ncRNAs). Long ncRNAs (lncRNAs) belong to a novel …

lncRNAs: insights into their function and mechanics in underlying disorders

X Li, Z Wu, X Fu, W Han - Mutation Research/Reviews in Mutation …, 2014 - Elsevier
Genomes of complex organisms are characterized by the pervasive expression of different
types of noncoding RNAs (ncRNAs). lncRNAs constitute a large family of long—arbitrarily …

A feedforward regulatory loop between HuR and the long noncoding RNA linc-MD1 controls early phases of myogenesis

I Legnini, M Morlando, A Mangiavacchi, A Fatica… - Molecular cell, 2014 - cell.com
The muscle-specific long noncoding RNA linc-MD1 was shown to be expressed during early
phases of muscle differentiation and to trigger the switch to later stages by acting as a …

Stem cell activation in skeletal muscle regeneration

X Fu, H Wang, P Hu - Cellular and molecular life sciences, 2015 - Springer
Muscle stem cell (satellite cell) activation post muscle injury is a transient and critical step in
muscle regeneration. It is regulated by physiological cues, signaling molecules, and …

Current and emerging treatment strategies for Duchenne muscular dystrophy

JK Mah - Neuropsychiatric disease and treatment, 2016 - Taylor & Francis
Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy in
childhood. It is caused by mutations of the DMD gene, leading to progressive muscle …

Roles of ncRNAs as ceRNAs in Gastric Cancer

J Ye, J Li, P Zhao - Genes, 2021 - mdpi.com
Although ignored in the past, with the recent deepening of research, significant progress has
been made in the field of non-coding RNAs (ncRNAs). Accumulating evidence has revealed …

MicroRNAs and long non-coding RNAs in genetic diseases

A Finotti, E Fabbri, I Lampronti, J Gasparello… - Molecular Diagnosis & …, 2019 - Springer
Since the discovery and classification of non-coding RNAs, their roles have gained great
attention. In this respect, microRNAs and long non-coding RNAs have been firmly …

Novel Long Noncoding RNAs (lncRNAs) in Myogenesis: a miR-31 Overlapping lncRNA Transcript Controls Myoblast Differentiation

M Ballarino, V Cazzella, D D'Andrea… - … and cellular biology, 2015 - Taylor & Francis
Transcriptome analysis allowed the identification of new long noncoding RNAs differentially
expressed during murine myoblast differentiation. These transcripts were classified on the …

[HTML][HTML] Landscape of RNAs in human lumbar disc degeneration

PH Lan, ZH Liu, YJ Pei, ZG Wu, Y Yu, YF Yang, X Liu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates noncoding RNAs (ncRNAs) fine-tune gene expression
with mysterious machinery. We conducted a combination of mRNA, miRNA, circRNA …