[HTML][HTML] Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy

V Subramaniyan, S Chakravarthi, R Jegasothy… - Toxicology reports, 2021 - Elsevier
One of the global burdens of health care is an alcohol-associated liver disease (ALD) and
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …

Advances in the concept of functional foods and feeds: applications of cinnamon and turmeric as functional enrichment ingredients

H Kumar, R Dhalaria, S Guleria, R Sharma… - Critical Reviews in …, 2023 - Taylor & Francis
Spices are a rich source of vitamins, polyphenols, proteins, dietary fiber, and minerals such
as calcium, magnesium, iron, and zinc, all of which play an important role in biological …

Anti-proliferative and immunomodulatory potencies of cinnamon oil on Ehrlich ascites carcinoma bearing mice

DS Morsi, SH El-Nabi, MA Elmaghraby, OA Abu Ali… - Scientific Reports, 2022 - nature.com
Cinnamon is a well-known natural spice and flavoring substance used worldwide. The
objective of the present work is to explore the possible antitumor and immunomodulatory …

Cinnamon aqueous extract attenuates diclofenac sodium and oxytetracycline mediated hepato-renal toxicity and modulates oxidative stress, cell apoptosis, and …

GE Elshopakey, ST Elazab - Veterinary Sciences, 2021 - mdpi.com
Among commonly consumed anti-inflammatory and antimicrobial drugs are diclofenac
sodium (DFS) and oxytetracycline (OTC), especially in developing countries because they …

Hepatoprotective and antioxidant effects of nanopiperine against Cypermethrin via mitigation of oxidative stress, inflammations and gene expression using qRT-PCR

S Hussain, AM Jali, S Alshahrani, KHM Khairat… - International journal of …, 2023 - mdpi.com
Cypermethrin (Cyp) is a pyrethroid that has been associated with the toxicity of various
organs. The aim of our study was to evaluate the hepatoprotective and antioxidant activities …

[HTML][HTML] Renoprotective effects of cinnamon oil against APAP-Induced nephrotoxicity by ameliorating oxidative stress, apoptosis and inflammation in rats

S Alshahrani, M Ashafaq, S Hussain… - Saudi Pharmaceutical …, 2021 - Elsevier
Acetaminophen (APAP) is used as a primary medication in relieving moderate pain and
fever. However, APAP is associated with toxic effects in renal tissue that appear because of …

Hepatic ZBTB22-mediated detoxification ameliorates acetaminophen-induced liver injury by inhibiting pregnane X receptor signaling

Y Chen, T Cui, S Xiao, T Li, Y Zhong, K Tang, J Guo… - Iscience, 2023 - cell.com
Overdose acetaminophen (APAP) can cause acute liver injury (ALI), but the underlying
mechanism remains undetermined. This study explored the role of hepatic Zinc Finger And …

Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in …

Y Lei, X Lei, A Zhu, S Xie, T Zhang, C Wang, A Song… - Molecules, 2023 - mdpi.com
Acetaminophen (APAP)-induced liver injury is a common hepatic disease resulting from
drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of …

Structure modification converts the hepatotoxic tacrine into novel hepatoprotective analogs

AA Sorour, RG Aly, HM Ragab, A Wahid - ACS omega, 2024 - ACS Publications
The liver is responsible for critical functions such as metabolism, secretion, storage,
detoxification, and the excretion of various compounds. However, there is currently no …

Neuroprotective Effects of Nano-Curcumin against Cypermethrin Associated Oxidative Stress and Up-Regulation of Apoptotic and Inflammatory Gene Expression in …

M Ashafaq, S Hussain, S Alshahrani, R Siddiqui… - Antioxidants, 2023 - mdpi.com
Cypermethrin (CPM) is the most toxic synthetic pyrethroid that has established neurotoxicity
through oxidative stress and neurochemical agitation in experimental rats. The toxic effects …