Pancreatic neuroendocrine neoplasms (PanNENs) are rare neoplasms arising from islets of
the Langerhans in the pancreas. They can be divided into two groups, based on peptide …

Pancreatic neuroendocrine neoplasms consist of heterogeneous diseases. Depending on
the novel features detected by various modern technologies, their classification and related …

Introduction Calcitonin-producing pancreatic neuroendocrine neoplasms (CT-pNENs) are
an extremely rare clinical entity, with approximately 60 cases reported worldwide. While CT …

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) account for 80% of
gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). GEP-NETs are well …

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell
carcinoma. Redox metabolism has been recognized as the hallmark of cancer. But the …

Importance Evidence-based treatment decisions for advanced gastroenteropancreatic
neuroendocrine neoplasms (GEP-NENs) require individualized patient-centered decision …

Abstract c-MYC is an important driver of high-risk neuroblastoma. A lack of c-MYC–driven
genetically engineered mouse models (GEMM) has hampered the ability to better …

Simple Summary Pancreatic neuroendocrine tumors are composite entities due to their
heterogeneity illustrated in clinical behavior, mutational pattern, and site of origin. Pancreatic …

High-throughput total nucleic acid (TNA) purification methods based on solid-phase
reversible immobilization (SPRI) beads produce TNA suitable for both genomic and …

Pancreatic neuroendocrine tumors (PanNETs) represent well-differentiated endocrine
neoplasms with variable clinical outcomes. Predicting patient outcomes using the current …