Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …

Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …

African apes harbour at least six Plasmodium species of the subgenus Laverania, one of
which gave rise to human Plasmodium falciparum. Here we use a selective amplification …

Reverse genetics is key to understanding protein function, but the mechanistic connection
between a gene of interest and the observed phenotype is not always clear. Here we …

Much of the virulence of Plasmodium falciparum malaria is caused by cytoadherence of
infected erythrocytes, which promotes parasite survival by preventing clearance in the …

The malaria parasite, Plasmodium, is one of the oldest parasites documented to infect
humans and has proven particularly hard to eradicate. One of the major hurdles in designing …

Malaria is caused by infection of erythrocytes by parasites of the genus Plasmodium. To
survive inside erythrocytes, these parasites induce sweeping changes within the host cell …

The recent decline in global malaria burden has stimulated efforts toward Plasmodium
falciparum elimination. Understanding the biology of malaria transmission stages may …

During its intraerythrocytic life cycle, the human malaria parasite Plasmodium falciparum
supplements its nutritional requirements by scavenging substrates from the plasma through …

Malaria parasites modify their human host cell, the mature erythrocyte. This modification is
mediated by a large number of parasite proteins that are exported to the host cell, and is …