Unravelling cell migration: defining movement from the cell surface

F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

A survey of physical methods for studying nuclear mechanics and mechanobiology

CM Hobson, MR Falvo, R Superfine - APL bioengineering, 2021 - pubs.aip.org
It is increasingly appreciated that the cell nucleus is not only a home for DNA but also a
complex material that resists physical deformations and dynamically responds to external …

Rigid tumours contain soft cancer cells

T Fuhs, F Wetzel, AW Fritsch, X Li, R Stange… - Nature Physics, 2022 - nature.com
Palpation utilizes the fact that solid breast tumours are stiffer than the surrounding tissue.
However, cancer cells tend to soften, which may enhance their ability to squeeze through …

Effects of electrical stimulation on skin surface

X Xu, H Zhang, Y Yan, J Wang, L Guo - Acta Mechanica Sinica, 2021 - Springer
Skin is the largest organ in the body, and directly contact with the external environment.
Articles on the role of micro-current and skin have emerged in recent years. The function of …

Reciprocal regulation of cellular mechanics and metabolism

TMJ Evers, LJ Holt, S Alberti, A Mashaghi - Nature metabolism, 2021 - nature.com
Metabolism and mechanics are intrinsically intertwined. External forces, sensed through the
cytoskeleton or distortion of the cell and organelles, induce metabolic changes in the cell …

[HTML][HTML] Targeting macrophage circadian rhythms with microcurrent stimulation to activate cancer immunity through phagocytic defense

Y Yoshida, T Tanihara, K Hamasaki, F Tsurusaki… - …, 2025 - pmc.ncbi.nlm.nih.gov
Rationale: Macrophage phagocytosis plays a role in cancer immunotherapy. The phagocytic
activity of macrophages, regulated by circadian clock genes, shows time-dependent …

Ion channels in gliomas—from molecular basis to treatment

AF Elias, BC Lin, BJ Piggott - International Journal of Molecular Sciences, 2023 - mdpi.com
Ion channels provide the basis for the nervous system's intrinsic electrical activity. Neuronal
excitability is a characteristic property of neurons and is critical for all functions of the …

Regulation of organelle size and organization during development

P Chen, DL Levy - Seminars in cell & developmental biology, 2023 - Elsevier
During early embryogenesis, as cells divide in the developing embryo, the size of
intracellular organelles generally decreases to scale with the decrease in overall cell size …

Modeling cells spreading, motility, and receptors dynamics: a general framework

M Serpelloni, M Arricca, C Bonanno, A Salvadori - Acta Mechanica Sinica, 2021 - Springer
The response of cells during spreading and motility is dictated by several multi-physics
events, which are triggered by extracellular cues and occur at different time-scales. For this …

Wide-range viscoelastic compression forces in microfluidics to probe cell-dependent nuclear structural and mechanobiological responses

MI Maremonti, V Panzetta… - Journal of the …, 2022 - royalsocietypublishing.org
The cell nucleus plays a critical role in mechanosensing and mechanotransduction
processes, by adaptive changes of its envelope composition to external biophysical stimuli …