Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …

Developing strategies toward safe and effective drug delivery into the central nervous
system (CNS) with improved targeting abilities and reduced off-target effects is crucial. CNS …

For over 40 years, attempts to develop treatments that protect neurons and other brain cells
against the cellular and biochemical consequences of cerebral ischaemia in acute …

The blood‐brain barrier (BBB) is a semipermeable and extremely selective system in the
central nervous system of most vertebrates, that separates blood from the brain's …

Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis causes cerebral dysfunction in the short and long term and induces …

The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …

The blood–brain barrier (BBB) is a specialized semipermeable structure that highly
regulates exchanges between the central nervous system parenchyma and blood vessels …

The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …