Task-dependent optimal representations for cerebellar learning

M Xie, SP Muscinelli, KD Harris, A Litwin-Kumar - Elife, 2023 - elifesciences.org
The cerebellar granule cell layer has inspired numerous theoretical models of neural
representations that support learned behaviors, beginning with the work of Marr and Albus …

Thousandfold cell-specific pharmacology of neurotransmission

BC Shields, H Yan, SSX Lim, SC Burwell, EA Fleming… - BioRxiv, 2022 - biorxiv.org
Cell-specific pharmaceutical technologies promise mechanistic insight into clinical
drugs―those that treat, and often define, human disease. In particular, DART (drug acutely …

Emergence of sparse representations from noise

T Bricken, R Schaeffer, B Olshausen, G Kreiman - 2023 - openreview.net
A hallmark of biological neural networks, which distinguishes them from their artificial
counterparts, is the high degree of sparsity in their activations. This discrepancy raises three …

How cerebellar architecture facilitates rapid online learning

AP Rotondo, DV Raman, T O'Leary - bioRxiv, 2022 - biorxiv.org
The cerebellum has a distinctive circuit architecture comprising the majority of neurons in the
brain. Marr-Albus theory and more recent extensions [,,,] demonstrate the utility of this …

[PDF][PDF] Contribution of cerebellar sensorimotor representations to behaviour

ER Palacios, ER Palacios - Clinical and …, 1998 - research-information.bris.ac.uk
The cerebellum is important for behavioural control. It is not necessary for the generation of
behaviour, but it is critical for its fluency and coordination. Its computations are often …