Cardiovascular disease in women: clinical perspectives

M Garcia, SL Mulvagh, CN Bairey Merz… - Circulation …, 2016 - Am Heart Assoc
Cardiovascular disease continues to be the leading cause of death among women in the
United States, accounting for≈ 1 of every 3 female deaths. Sex-specific data focused on …

Gender differences in the effects of cardiovascular drugs

J Tamargo, G Rosano, T Walther… - European Heart …, 2017 - academic.oup.com
An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

Sex differences in the cardiovascular consequences of diabetes mellitus: a scientific statement from the American Heart Association

JG Regensteiner, S Golden, AG Huebschmann… - Circulation, 2015 - Am Heart Assoc
For years, it has been recognized that the incidence of coronary heart disease (CHD) in
women lags behind that of men by≈ 10 years, 7 thus generating hypotheses that …

[HTML][HTML] Complications of diabetes

K Papatheodorou, M Banach, M Edmonds… - Journal of diabetes …, 2015 - ncbi.nlm.nih.gov
Diabetes is justly recognized as an emerging global epidemic, representing one of the
leading causes of morbidity and mortality worldwide. Hyperglycemia, the common …

Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese …

AA Houde, C Légaré, S Biron, O Lescelleur… - BMC medical …, 2015 - Springer
Background Leptin (LEP) and adiponectin (ADIPOQ) genes encode adipokines that are
mainly secreted by adipose tissues, involved in energy balance and suspected to play a role …

Novel imaging biomarkers: epicardial adipose tissue evaluation

CB Monti, M Codari, CN De Cecco… - The British journal of …, 2020 - academic.oup.com
Epicardial adipose tissue (EAT) is a metabolically activated beige adipose tissue, non-
homogeneously surrounding the myocardium. Physiologically, EAT regulates toxic fatty …

Novel insights into the pathophysiology and clinical aspects of diabetic nephropathy

Z Ilyas, JT Chaiban, A Krikorian - Reviews in Endocrine and Metabolic …, 2017 - Springer
Diabetic nephropathy (DN) is a well-described complication of diabetes mellitus and the
leading cause of end stage renal disease (ESRD). Although increased albuminuria has …

Sex-gender-related therapeutic approaches for cardiovascular complications associated with diabetes

I Campesi, F Franconi, G Seghieri, M Meloni - Pharmacological Research, 2017 - Elsevier
Diabetes is a chronic disease associated with micro-and macrovascular complications and
is a well-established risk factor for cardiovascular disease. Cardiovascular complications …

[HTML][HTML] Statin therapy is not warranted for a person with high LDL-cholesterol on a low-carbohydrate diet

DM Diamond, BT Bikman, P Mason - Current Opinion in …, 2022 - journals.lww.com
Extensive research has demonstrated the efficacy of the LCD to improve the most robust
CVD risk factors, such as hyperglycemia, hypertension, and atherogenic dyslipidemia. Our …

A novel chemically engineered multifunctional statin conjugate as self-assembled nanoparticles inhibiting bile acid transporters

KJ Lee, YM Lee, SB Yang, JH Lee, HR Kim… - Journal of Controlled …, 2024 - Elsevier
Statins are widely used to treat hyperlipidemia; however, their mechanism—inhibiting
cholesterol production without promoting its utilization—causes problems, such as inducing …