We provide the first analysis and synthesis of the evolutionary and mechanistic bases for risk
of endometriosis in humans, structured around Niko Tinbergen's four questions about …

The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout
the menstrual cycle in response to ovarian hormones. We have generated dense single-cell …

Menstrual cycle length and modern living: a review : Current Opinion in Endocrinology,
Diabetes and Obesity Menstrual cycle length and modern living: a review : Current Opinion in …

Genome-wide association studies (GWAS) have been used to study the genetic basis of a
wide variety of complex diseases and other traits. We describe UK Biobank GWAS results for …

Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using
data from large endometriosis and EOC genome-wide association meta-analyses, we …

The present study was designed to examine whether sex hormone polymorphisms proven
by GWAS are associated with endometriosis risk. Unrelated female participants totaling …

STUDY QUESTION Which genetic factors regulate female propensity for giving birth to
spontaneous dizygotic (DZ) twins? SUMMARY ANSWER We identified four new loci …

BACKGROUND The human female reproductive lifespan is regulated by the dynamics of
ovarian function, which in turn is influenced by several factors: from the basic molecular …

Chronic pelvic pain represents a major public health problem for women and impacts
significantly on their quality of life. Yet it is under‐researched and a challenge to manage …

There is substantial genetic variation for common traits associated with reproductive lifespan
and for common diseases influencing female fertility. Progress in high-throughput …