Oxysterols (oxidized derivatives of cholesterol and phytosterols) can be generated in the
human organism through different oxidation processes, some requiring enzymes …

Insects have evolved a powerful detoxification system to protect themselves against
environmental and anthropogenic xenobiotics including pesticides and nanoparticles. The …

In Québec, as observed globally, abnormally high honey bee mortality rates have been
reported recently. Several potential contributing factors have been identified, and exposure …

High level resistance for a variety of insecticides has emerged in Bemisia tabaci, a globally
notorious insect. Neonicotinoid insecticides have been applied widely to control B. tabaci …

The use of Drosophila melanogaster for studies of toxicology has grown considerably in the
last decade. The Drosophila model has long been appreciated as a versatile and powerful …

Target insensitivity contributing to imidacloprid resistance in Nilaparvata lugens has been
reported to occur either through point mutations or quantitative change in nicotinic …

Abstract Background Cytochrome P450s (CYPs) in animals fall into two categories: those
that synthesize or metabolize endogenous molecules and those that interact with …

Abstract Fall armyworm, Spodoptera frugiperda (Smith), has caused significant losses for
crop production in China. The fall armyworm is mainly controlled by the chemical …

Modifications of metabolic pathways are important in insecticide resistance evolution.
Mutations leading to changes in expression levels or substrate specificities of cytochrome …

Background Several interventions increase lifespan in model organisms, including reduced
insulin/insulin-like growth factor-like signaling (IIS), FOXO transcription factor activation …