Nanoscale LC–MS(n): technical design and applications to peptide and protein analysis

HD Meiring, E Van der Heeft… - Journal of …, 2002 - Wiley Online Library
We describe a nanoscale capillary column switching HPLC–ESI/MS (n) system in detail. It is
intended for routine operation with 50 μm ID packed, fused silica columns. The system …

Capillary electrophoresis–mass spectrometry: 15 years of developments and applications

P Schmitt‐Kopplin, M Frommberger - Electrophoresis, 2003 - Wiley Online Library
Since its introduction in 1987, capillary electrophoresis‐mass spectrometry (CE‐MS) has
developed to a well accepted multidimensional analytical approach complementary and/or …

Simplified capillary electrophoresis nanospray sheath‐flow interface for high efficiency and sensitive peptide analysis

R Wojcik, OO Dada, M Sadilek… - … in Mass Spectrometry, 2010 - Wiley Online Library
We report a simple nanospray sheath‐flow interface for capillary electrophoresis. This
interface relies on electrokinetic flow to drive both the separation and the electrospray; no …

Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue

SK Sze, Y Ge, HB Oh… - Proceedings of the …, 2002 - National Acad Sciences
A mass difference between the measured molecular weight of a protein and that of its DNA-
predicted sequence indicates sequence errors and/or posttranslational modifications. In the …

Twenty years of interface development for capillary electrophoresis–electrospray ionization–mass spectrometry

EJ Maxwell, DDY Chen - Analytica chimica acta, 2008 - Elsevier
Capillary electrophoresis–electrospray ionization–mass spectrometry has the potential to
become a preferred tool for the analysis of biological mixtures and other complex samples …

Subfemtomole MS and MS/MS peptide sequence analysis using nano-HPLC micro-ESI fourier transform ion cyclotron resonance mass spectrometry

SE Martin, J Shabanowitz, DF Hunt… - Analytical …, 2000 - ACS Publications
Subfemtomole peptide sequence analysis has been achieved using microcapillary HPLC
columns, with integrated nanoelectrospray emitters, coupled directly to a Fourier transform …

Microfluidic capillary electrophoresis–mass spectrometry for analysis of monosaccharides, oligosaccharides, and glycopeptides

K Khatri, JA Klein, JR Haserick, DR Leon… - Analytical …, 2017 - ACS Publications
Glycomics and glycoproteomics analyses by mass spectrometry require efficient front-end
separation methods to enable deep characterization of heterogeneous glycoform …

Affinity capillary electrophoresis: important application areas and some recent developments

NHH Heegaard, S Nilsson, NA Guzman - Journal of Chromatography B …, 1998 - Elsevier
Affinity capillary electrophoresis (ACE) is a broad term referring to the separation by capillary
electrophoresis of substances that participate in specific or non-specific affinity interactions …

Recent advances in capillary electrophoresis/electrospray‐mass spectrometry

A Von Brocke, G Nicholson, E Bayer - Electrophoresis, 2001 - Wiley Online Library
In this review, the progress in hyphenation of capillary electrophoresis (CE) with
electrospray ionization‐mass spectrometry (ESI‐MS) since the article of Banks (Banks, JF …

Capillary electrophoresis–electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments

G Bonvin, J Schappler, S Rudaz - Journal of Chromatography A, 2012 - Elsevier
Capillary electrophoresis (CE) hyphenated to electrospray ionization (ESI) mass
spectrometry (MS) is a powerful tool for analyzing a wide variety of analytes in different …