Neuroinflammatory mediators in acquired epilepsy: an update
Epilepsy is a group of chronic neurological disorders that have diverse etiologies but are
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …
Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies
W Li, J Wu, Y Zeng, W Zheng - Frontiers in Immunology, 2023 - frontiersin.org
Epilepsy is a group of enduring neurological disorder characterized by spontaneous and
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …
Ablation of Siglec-E augments brain inflammation and ischemic injury
Sialic acid immunoglobulin-like lectin E (Siglec-E) is a subtype of pattern recognition
receptors found on the surface of myeloid cells and functions as a key immunosuppressive …
receptors found on the surface of myeloid cells and functions as a key immunosuppressive …
The mechanisms of minocycline in alleviating ischemic stroke damage and cerebral ischemia-reperfusion injury
K Zhao, P Wang, X Tang, N Chang, H Shi, L Guo… - European Journal of …, 2023 - Elsevier
Stroke is a group of diseases resulting from cerebral vascular rupture or obstruction and
subsequent brain blood circulation disorder, leading to rapid neurological deficits. Ischemic …
subsequent brain blood circulation disorder, leading to rapid neurological deficits. Ischemic …
Complementary roles of EP2 and EP4 receptors in malignant glioma
Abstract Background and Purpose Glioblastoma (GBM) is the most aggressive brain tumour
in the central nervous system, but the current treatment is very limited and unsatisfactory …
in the central nervous system, but the current treatment is very limited and unsatisfactory …
Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective
Status epilepticus (SE) in humans is characterized by prolonged convulsive seizures that
are generalized and often difficult to control. The current antiseizure drugs (ASDs) aim to …
are generalized and often difficult to control. The current antiseizure drugs (ASDs) aim to …
[HTML][HTML] Prostaglandin E2 in neuroblastoma: Targeting synthesis or signaling?
Neuroblastoma (NB) is the most common pediatric extracranial solid tumor arising from
neural crest cells of the developing sympathetic nervous system. Despite marked advances …
neural crest cells of the developing sympathetic nervous system. Despite marked advances …
[HTML][HTML] Cross-talk between bioactive lipid mediators and the unfolded protein response in ischemic stroke
T Teder, JZ Haeggström, M Airavaara… - Prostaglandins & Other …, 2023 - Elsevier
Ischemic cerebral stroke is a severe medical condition that affects about 15 million people
every year and is the second leading cause of death and disability globally. Ischemic stroke …
every year and is the second leading cause of death and disability globally. Ischemic stroke …
Anti-inflammatory activity of d-pinitol possibly through inhibiting COX-2 enzyme: in vivo and in silico studies
Introduction: D-pinitol, a naturally occurring inositol, has diverse biological activities like
antioxidant, antimicrobial and anticancer activities. This study aimed to evaluate anti …
antioxidant, antimicrobial and anticancer activities. This study aimed to evaluate anti …
Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
Summary Prostaglandin E 2 (PGE 2) promotes tumor cell proliferation, migration, and
invasion, fostering an inflammation-enriched microenvironment that facilitates angiogenesis …
invasion, fostering an inflammation-enriched microenvironment that facilitates angiogenesis …