Reperfusion injury is still a major challenge that impedes neuronal survival in ischemic
stroke. However, the current clinical treatments are remained on single pathological …

A brain-targeting nanodelivery system has been a hot topic and has undergone rapid
progression. However, due to various obstacles such as the intestinal epithelial barrier (IEB) …

Fingolimod (FTY720) is an oral drug approved by the Food and Drug Administration (FDA)
for management of multiple sclerosis (MS) symptoms, which has also shown beneficial …

Background & Aims Hepatopulmonary syndrome (HPS) is characterised by a defect in
arterial oxygenation induced by pulmonary vascular dilatation in patients with liver disease …

Multiple sclerosis (MS) is a chronic disease that affects the central nervous system and is
characterized by inflammation, demyelination, and degenerative changes. Relapsing …

Background Fingolimod and ocrelizumab are approved treatments for adults with multiple
sclerosis (MS); however, only fingolimod is FDA-approved for the treatment of pediatric MS …

Copper and zinc are essential elements that aid in various physiological and biochemical
functions. Nevertheless, exposure to these heavy metals could also be detrimental to some …

Natural additives are crucial to maintaining healthy aquaculture practices as they boost fish
wellness, reduce related environmental problems, and improve productivity. The current …

Abstract Object: Fingomolid (FTY720), an immunosuppressive agent, was found to protect
the retina against light stress in our previous study. In this study, we investigate whether …

Background and purpose: Fingolimod, is one of the first oral disease-modifying treatments
(DMT) that has shown efficacy in advanced clinical trials for the treatment of multiple …