Obesity and cancer: existing and new hypotheses for a causal connection

TW Stone, M McPherson, LG Darlington - EBioMedicine, 2018 - thelancet.com
Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of
dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

The disease burden associated with overweight and obesity

A Must, J Spadano, EH Coakley, AE Field, G Colditz… - Jama, 1999 - jamanetwork.com
ContextOverweight and obesity are increasing dramatically in the United States and most
likely contribute substantially to the burden of chronic health conditions. ObjectiveTo …

Antioxidant role of kaempferol in prevention of hepatocellular carcinoma

N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

Obesity and colorectal cancer

M Bardou, AN Barkun, M Martel - Gut, 2013 - gut.bmj.com
Excess body weight, as defined by the body mass index (BMI), has been associated with
several diseases and includes subjects who are overweight (BMI≥ 25–29.9 kg/m2) or …

Oxidative stress and liver cancer: etiology and therapeutic targets

Z Wang, Z Li, Y Ye, L Xie, W Li - Oxidative medicine and …, 2016 - Wiley Online Library
Accumulating evidence has indicated that oxidative stress (OS) is associated with the
development of hepatocellular carcinoma (HCC). However, the mechanisms remain largely …

The growing challenge of obesity and cancer: an inflammatory issue

AE Harvey, LM Lashinger… - Annals of the New York …, 2011 - Wiley Online Library
The prevalence of obesity, an established risk factor for many cancers, has risen steadily for
the past several decades in the United States and in many parts of the world. This review …

[HTML][HTML] Obesity and colorectal cancer: role of adipokines in tumor initiation and progression

S Riondino, M Roselli, R Palmirotta… - World journal of …, 2014 - ncbi.nlm.nih.gov
Obesity-associated diseases account for a large portion of public health challenges. Among
obesity-related disorders, a direct and independent relationship has been ascertained for …

[PDF][PDF] Inflammatory and metabolic biomarkers and risk of liver and biliary tract cancer

K Aleksandrova, H Boeing, U Nöthlings, M Jenab… - …, 2014 - Wiley Online Library
Obesity and associated metabolic disorders have been implicated in liver carcinogenesis;
however, there are little data on the role of obesity‐related biomarkers on liver cancer risk …

Mechanisms linking obesity, inflammation and altered metabolism to colon carcinogenesis

E Yehuda‐Shnaidman, B Schwartz - obesity reviews, 2012 - Wiley Online Library
Due to its prevalence, obesity is now considered a global epidemic. It is linked to increased
risk of colorectal cancer, the third most common cancer and the second leading cause of …