In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology

S Bibi, I Ullah, B Zhu, M Adnan, R Liaqat, WB Kong… - Scientific reports, 2021 - nature.com
Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …

Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

The Candidate Antigens to Achieving an Effective Vaccine against Staphylococcus aureus

HR Jahantigh, S Faezi, M Habibi, M Mahdavi… - Vaccines, 2022 - mdpi.com
Staphylococcus aureus (S. aureus) is an opportunistic pathogen that causes various
inflammatory local infections, from those of the skin to postinfectious glomerulonephritis …

A review on the development of bacterial multi-epitope recombinant protein vaccines via reverse vaccinology

Y Li, MHR Farhan, X Yang, Y Guo, Y Sui, J Chu… - International Journal of …, 2024 - Elsevier
Bacterial vaccines play a crucial role in combating bacterial infectious diseases. Apart from
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …

A cutting-edge immunoinformatics approach for design of multi-epitope oral vaccine against dreadful human malaria

M Pritam, G Singh, S Swaroop, AK Singh… - International Journal of …, 2020 - Elsevier
Human malaria is a pathogenic disease mainly caused by Plasmodium falciparum, which
was responsible for about 405,000 deaths globally in the year 2018. To date, several …

In-silico design and evaluation of an epitope-based serotype-independent promising vaccine candidate for highly cross-reactive regions of pneumococcal surface …

E Afshari, RA Cohan… - Journal of Translational …, 2023 - Springer
Background The pathogenicity of pneumococcus with high morbidity, mortality, and multi-
drug resistance patterns has been increasing. The limited coverage of the licensed …

Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction

AS Mubarak, ZS Ameen, AS Hassan, DU Ozsahin - Scientific Reports, 2024 - nature.com
Tuberculosis (TB) a disease caused by Mycobacterium tuberculosis (Mtb) poses a
significant threat to human life, and current BCG vaccinations only provide sporadic …

In silico identification of epitope-based vaccine candidates against HTLV-1

HR Jahantigh, A Stufano, P Lovreglio… - Journal of …, 2022 - Taylor & Francis
Human T cell leukemia virus type 1 (HTLV-1) is a positive single-stranded RNA virus
belonging to the delta retrovirus family. It was the first retrovirus reported to be associated …

A new candidate epitope-based vaccine against PspA PhtD of Streptococcus pneumoniae: a computational experimental approach

M Shafaghi, Z Bahadori, SM Barzi, E Afshari… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Pneumococcus is an important respiratory pathogen that is associated with high
rates of death in newborn children and the elderly. Given the disadvantages of current …

Design of multi-epitope vaccine candidate based on OmpA, CarO and ZnuD proteins against multi-drug resistant Acinetobacter baumannii

B Negahdari, P Sarkoohi, B Shahbazi, K Ahmadi - Heliyon, 2024 - cell.com
Acinetobacter baumannii has been identified as a major cause of nosocomial infections.
Acinetobacter infections are often difficult to treat with multidrug resistant phenotypes. One of …