The heart hypertrophies in response to developmental signals as well as increased
workload. Although adult-onset hypertrophy can ultimately lead to disease, cardiac …

The athlete's heart is a well-known phenomenon in adults practising competitive sports.
Unfortunately, to date, most of the studies on training-induced cardiac remodelling have …

Sports Cardiology practice commonly involves the evaluation of athletes for genetically
determined cardiac conditions that may predispose to malignant arrhythmias, heart failure …

Ion channels in the myocardial cellular membrane are responsible for allowing the cardiac
action potential. Genetic abnormalities in these channels can predispose to life-threatening …

Pediatric cardiomyopathies (CMs) and electrical diseases constitute a heterogeneous
spectrum of disorders distinguished by structural and electrical abnormalities in the heart …

Background: Heart disease is a major cause of death in industrialized nations, with
approximately 50% of these deaths attributable to sudden cardiac arrest. If patients at high …

Sudden cardiac death (SCD) in a young athlete represents a dramatic event, and an
increasing number of medico-legal cases have addressed this topic. In addition to …

Recent advances in next-genetic sequencing technology have facilitated an expansion in
the use of exome and genome sequencing in the research and clinical settings. While this …

Pediatric sudden cardiac death (SCD) is the sudden unexpected death of a child or
adolescent due to a presumed cardiac etiology. Heritable causes of pediatric SCD are …

Brugada syndrome (BrS) is an autosomal dominant inherited channelopathy. It is associated
with a typical pattern of ST-segment elevation in the precordial leads V1–V3 and potentially …