The mammary gland (MG) is an exocrine gland present in female mammals responsible for
the production and secretion of milk during the process of lactation. It is mainly composed by …

Several studies have made strong efforts to understand how age and parity modulate the
risk of breast cancer. A holistic understanding of the dynamic regulation of the …

Breast cancer occurring during pregnancy (PrBC) and postpartum (PPBC) is usually
diagnosed at more advanced stages compared with other breast cancer, worsening its …

Simple Summary In breast cancer, there is a high degree of variability in tumors and the
surrounding tissue called the tumor microenvironment (TME). To better understand tumor …

The IL-6 cytokine family is a group of signaling molecules with wide expression and function
across vertebrates. Each member of the family signals by binding to its specific receptor and …

The pattern of delayed recurrence in a subset of breast cancer patients has long been
explained by a model that incorporates a variable period of cellular or tumor mass dormancy …

Female breast cancer emerged as the leading cancer type in terms of incidence globally in
2020. Although mortality due to breast cancer has improved during the past three decades …

Background Formalin-fixed, paraffin-embedded (FFPE) tissues for RNA-seq have
advantages over fresh frozen tissue including abundance and availability, connection to rich …

Importance Breast cancer diagnosed within 5 to 10 years after childbirth, calledpostpartum
breast cancer (PPBC), is associated with increased risk for metastasis and death. Whether a …

Childbirth at any age confers a transient increased risk for breast cancer in the first decade
postpartum and this window of adverse effect extends over two decades in women with late …