Genetics of circadian rhythms and sleep in human health and disease

JM Lane, J Qian, E Mignot, S Redline… - Nature Reviews …, 2023 - nature.com
Circadian rhythms and sleep are fundamental biological processes integral to human
health. Their disruption is associated with detrimental physiological consequences …

[HTML][HTML] Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms

H Zou, H Zhou, R Yan, Z Yao, Q Lu - Frontiers in neuroscience, 2022 - frontiersin.org
The circadian rhythm is crucial for physiological and behavioral functions. Chronotype,
which represents individual preferences for activity and performance, is associated with …

Orexin 2 receptor–selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients

R Evans, H Kimura, R Alexander… - Proceedings of the …, 2022 - National Acad Sciences
Narcolepsy type 1 (NT1) is a sleep disorder caused by a loss of orexinergic neurons.
Narcolepsy type 2 (NT2) is heterogeneous; affected individuals typically have normal orexin …

Sensing with earables: A systematic literature review and taxonomy of phenomena

T Röddiger, C Clarke, P Breitling… - Proceedings of the …, 2022 - dl.acm.org
Earables have emerged as a unique platform for ubiquitous computing by augmenting ear-
worn devices with state-of-the-art sensing. This new platform has spurred a wealth of new …

[HTML][HTML] Poor sleep and shift work associate with increased blood pressure and inflammation in UK Biobank participants

M Kanki, AP Nath, R Xiang, S Yiallourou… - Nature …, 2023 - nature.com
Disrupted circadian rhythms have been linked to an increased risk of hypertension and
cardiovascular disease. However, many studies show inconsistent findings and are not …

[HTML][HTML] Redox changes in obesity, metabolic syndrome, and diabetes

B Korac, A Kalezic, V Pekovic-Vaughan, A Korac… - Redox Biology, 2021 - Elsevier
Abstract" Life is an instantaneous encounter of circulating matter and flowing energy"(Jean
Giaja, Serbian physiologist), is one of the most elegant definitions not only of life but the …

Baseline vitamin D status, sleep patterns, and the risk of incident type 2 diabetes in data from the UK Biobank study

M Wang, T Zhou, X Li, H Ma, Z Liang… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Circulating vitamin D concentrations have been associated with the risk of type
2 diabetes (T2D), but the results are inconsistent. Emerging evidence suggests that vitamin …

[HTML][HTML] Genetic determinants of daytime napping and effects on cardiometabolic health

HS Dashti, I Daghlas, JM Lane, Y Huang… - Nature …, 2021 - nature.com
Daytime napping is a common, heritable behavior, but its genetic basis and causal
relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide …

[HTML][HTML] Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank

M Wainberg, SE Jones, LM Beaupre, SL Hill… - PLoS …, 2021 - journals.plos.org
Background Sleep problems are both symptoms of and modifiable risk factors for many
psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep at …

The association between sleep and depressive symptoms in US adults: data from the NHANES (2007–2014)

L Chunnan, S Shaomei, L Wannian - Epidemiology and Psychiatric …, 2022 - cambridge.org
Aims To assess the association of sleep factors (sleep duration, trouble sleeping, sleep
disorder) and combined sleep behaviours with the risk of clinically relevant depression …