Poxviruses, of which vaccinia virus is the prototype, are a large family of double-stranded
DNA viruses that replicate exclusively in the cytoplasm of infected cells. This physical and …

As opportunistic pathogens, viruses have evolved many elegant strategies to manipulate
host cells for infectious entry and replication. Viral apoptotic mimicry, defined by the …

Correlative electron and fluorescence microscopy has the potential to elucidate the
ultrastructural details of dynamic and rare cellular events, but has been limited by low …

Viruses intricately interact with and modulate cellular membranes at several stages of their
replication, but much less is known about the role of viral lipids compared to proteins and …

This review summarizes recent structural and molecular biology studies related to the
morphogenesis of African swine fever virus (ASFV). ASFV possesses icosahedral …

Singapore grouper iridovirus (SGIV), one of the nucleocytoviricota viruses (NCVs), is a
highly pathogenic iridovirid. SGIV infection results in massive economic losses to the …

The endoplasmic reticulum (ER) is the largest intracellular organelle. It forms a complex
network of continuous sheets and tubules, extending from the nuclear envelope (NE) to the …

During its cytoplasmic replication, vaccinia virus assembles non-infectious spherical
immature virions (IV) coated by a viral D13 lattice. Subsequently, IV mature into infectious …

Viruses: From Understanding to Investigation, Second Edition presents the definitions and
unique characteristics of viruses. The book includes major topics such as virus lifecycle …

Replication and assembly of many viruses occur in specific intracellular compartments
known as 'virus factories'. Our knowledge of the biogenesis and architecture of these unique …