Architecture of the entorhinal cortex a review of entorhinal anatomy in rodents with some comparative notes

MP Witter, TP Doan, B Jacobsen, ES Nilssen… - Frontiers in systems …, 2017 - frontiersin.org
The entorhinal cortex (EC) is the major input and output structure of the hippocampal
formation, forming the nodal point in cortico-hippocampal circuits. Different division schemes …

The representation of space in the brain

RM Grieves, KJ Jeffery - Behavioural processes, 2017 - Elsevier
Animals can navigate vast distances and often display behaviours or activities that indicate a
detailed, internal spatial representation of their surrounding environment or a 'cognitive …

Entorhinal cortex directs learning-related changes in CA1 representations

C Grienberger, JC Magee - Nature, 2022 - nature.com
Learning-related changes in brain activity are thought to underlie adaptive behaviours,. For
instance, the learning of a reward site by rodents requires the development of an over …

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

D Franjic, M Skarica, S Ma, JI Arellano… - Neuron, 2022 - cell.com
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …

Neurons and networks in the entorhinal cortex: A reappraisal of the lateral and medial entorhinal subdivisions mediating parallel cortical pathways

ES Nilssen, TP Doan, MJ Nigro, S Ohara… - …, 2019 - Wiley Online Library
In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the
entorhinal cortex with a focus on the concept of parallel cortical connectivity streams. The …

Microcircuits for spatial coding in the medial entorhinal cortex

JJ Tukker, P Beed, M Brecht, R Kempter… - Physiological …, 2022 - journals.physiology.org
The hippocampal formation is critically involved in learning and memory and contains a
large proportion of neurons encoding aspects of the organism's spatial surroundings. In the …

Sparse activity of identified dentate granule cells during spatial exploration

M Diamantaki, M Frey, P Berens, P Preston-Ferrer… - Elife, 2016 - elifesciences.org
In the dentate gyrus–a key component of spatial memory circuits–granule cells (GCs) are
known to be morphologically diverse and to display heterogeneous activity profiles during …

A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory

Y Ben-Simon, K Kaefer, P Velicky, J Csicsvari… - Nature …, 2022 - nature.com
The mammalian hippocampal formation (HF) plays a key role in several higher brain
functions, such as spatial coding, learning and memory. Its simple circuit architecture is often …

A map-like micro-organization of grid cells in the medial entorhinal cortex

Y Gu, S Lewallen, AA Kinkhabwala, C Domnisoru… - Cell, 2018 - cell.com
How the topography of neural circuits relates to their function remains unclear. Although
topographic maps exist for sensory and motor variables, they are rarely observed for …

The hippocampus in depth: a sublayer-specific perspective of entorhinal–hippocampal function

M Valero, LM de la Prida - Current opinion in neurobiology, 2018 - Elsevier
Highlights•We review classical ideas on entorhinal–hippocampal structure and
function.•Recent data on cell-type specific entorhinal inputs radically change these …