Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

Tumours with an immunosuppressive microenvironment respond poorly to therapy.
Activation of the stimulator of interferon genes (STING) pathway can enhance intratumoural …

Hydrophilic polymeric networks that are capable of imbibing huge volumes of water and
undergoing swelling and shrinkage suitably to facilitate controlled drug-release are called …

The activation of the cGAS-STING pathway has tremendous potential to improve anti-tumor
immunity by generating type I interferons. In recent decades, we have witnessed that …

Over the past decade, preclinical and clinical research have confirmed the essential role of
interferons for effective host immunological responses to malignant cells. Type I interferons …

Immune checkpoint inhibitors (ICI) have revolutionised cancer therapy. However, they have
been effective in only a small subset of patients and a principal mechanism underlying …

Hydrogels are water-swollen three-dimensional networks made of polymers, proteins, small
molecules or colloids. They constitute a versatile platform for drug delivery because of their …

Activation of the stimulator of interferon gene (STING) pathway within the tumor
microenvironment has been shown to generate a strong antitumor response. Although local …

Self-assembly is a growth mechanism in nature to apply local interactions forming a
minimum energy structure. Currently, self-assembled materials are considered for …