Acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency
virus (HIV), is one of the leading causes of human deaths. The advent of different anti-HIV …

Indole is known as a versatile heterocyclic building block for its multiple pharmacological
activities and has a high probability of success in the race for drug candidates. Many natural …

Background: Studies on the interaction between bioactive molecules and HIV-1 virus have
been the focus of recent research in the scope of medicinal chemistry and pharmacology …

A highly efficient catalyst–base pair for the C–H arylation of free (NH)-indoles in the C-3
position is reported. Ligand-free palladium acetate coupled with lithium …

Allosteric integrase inhibitors (ALLINIs) are a class of experimental anti-HIV agents that
target the noncatalytic sites of the viral integrase (IN) and interfere with the IN-viral RNA …

Allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are a promising new class of antiretroviral
agents that disrupt proper viral maturation by inducing hyper-multimerization of IN. Here we …

The spread of Human Immunodeficiency Virus (HIV) still represents a global public health
issue of major concern, and would benefit from unveiling unique viral features as targets for …

3, 4-Dihydroquinolone is an important drug and biological compound. o-
Halophenylacrylamides were cyclized by two-electron reduction under electrochemical …

A palladium–dihydroxyterphenylphosphine (DHTP) catalyst was successfully applied to the
direct C3-arylation of N-unsubstituted indoles with aryl chlorides, triflates, and nonaflates …

ABSTRACT HIV-1 elite controllers (EC) are a rare group among HIV-1-infected individuals
who can naturally control viral replication for a prolonged period. Due to their …