Sulfonamide moiety as “molecular chimera” in the design of new drugs
G Culletta, M Tutone, M Zappalà… - Current Medicinal …, 2023 - benthamdirect.com
Background: The-SO2NH-group is of great significance in modern pharmaceutical use
since, in sulfa-drugs, it is possible to introduce easily chemical modifications, and even small …
since, in sulfa-drugs, it is possible to introduce easily chemical modifications, and even small …
Antiultraviolet, Antioxidant, and Antimicrobial Properties and Anticancer Potential of Novel Environmentally Friendly Amide-Modified Gallic Acid Derivatives
X Wang, J Cong, L Zhang, Z Han… - Journal of Agricultural …, 2023 - ACS Publications
Polyphenols and amides isolated from natural products have various biological functions,
such as antioxidant, antimicrobial, anticancer, and antiviral activities, and they are widely …
such as antioxidant, antimicrobial, anticancer, and antiviral activities, and they are widely …
Anticancer Study on IrIII and RhIII Half-Sandwich Complexes with the Bipyridylsulfonamide Ligand
M Kowalik, J Masternak, M Olszewski… - Inorganic …, 2024 - ACS Publications
Organometallic half-sandwich complexes [(η5-Cp) IrCl (L)] PF6 (1) and [(η5-Cp) RhCl (L)]
PF6 (2) were prepared using pentamethylcyclopentadienyl chloride dimers of iridium (III) or …
PF6 (2) were prepared using pentamethylcyclopentadienyl chloride dimers of iridium (III) or …
A facile synthesis, drug-likeness, and in silico molecular docking of certain new azidosulfonamide–chalcones and their in vitro antimicrobial activity
M Mustafa, YA Mostafa - Monatshefte für Chemie-Chemical Monthly, 2020 - Springer
New azidosulfonamide–chalcone derivatives were designed and synthesized. Their
structures were elucidated by 1 H and 13 C NMR spectral analyses, in addition to elemental …
structures were elucidated by 1 H and 13 C NMR spectral analyses, in addition to elemental …
Construction of Aryl Azide‐ and Triazole‐Based Unnatural Amino Acid Motifs via the Pd(II)‐Catalyzed C(sp3)−H Arylation
S Suwasia, S Arulananda Babu - European Journal of Organic …, 2024 - Wiley Online Library
This paper reports a method for the synthesis of examples of aryl azide‐and triazole moiety‐
based unnatural amino acid motifs using the Pd (II)‐catalyzed arylation of the prochiral C …
based unnatural amino acid motifs using the Pd (II)‐catalyzed arylation of the prochiral C …
Development of new hetero-steroid hybrids with antiproliferative activity against MCF-7 breast cancer cells
In continuation of our efforts to develop new antiproliferative agents that could be effective
and selective in treatment of cancer, we designed and synthesized new hybrid structures …
and selective in treatment of cancer, we designed and synthesized new hybrid structures …
A Newly Synthesized β-amino-α, β-unsaturated Ketone Derivative of β-himachalene: Structural, NBO, NLO, and Molecular Docking Studies
MA El Had - 2022 - digibug.ugr.es
In the current study, a new β-amino-α, β-unsaturated ketone-based himachalene ((1S, 3R,
8R)-9-amino-2, 2-dichloro-3, 7, 7, 10-tetramethyltricyclo [6.4. 0.01, 3] dodec-9-en-11-one)(4) …
8R)-9-amino-2, 2-dichloro-3, 7, 7, 10-tetramethyltricyclo [6.4. 0.01, 3] dodec-9-en-11-one)(4) …
Biological Evaluation of Azide Derivative as Antibacterial and Anticancer Agents
Azides are significant compounds because of their biological effects on bacteria, viruses,
fungi, and cancer. The antibacterial and anticancer properties of azide derivatives have …
fungi, and cancer. The antibacterial and anticancer properties of azide derivatives have …
Synthesis and Antibacterial evaluation of N-(2-(1-Aryl-1H-1, 2, 3-triazol-4-yl) propan-2-yl) benzene sulfonamides.
R Luxmi, CP Kaushik, M Chahal - Chemistry & Biology …, 2021 - search.ebscohost.com
A series of twenty four sulfonamide linked disubstituted 1, 2, 3-triazoles wasdesigned and
synthesized via click reaction using 4-substituted-N-(2-methylbut-3-yn-2-yl) …
synthesized via click reaction using 4-substituted-N-(2-methylbut-3-yn-2-yl) …