Process intensification offers the potential to drastically reduce the energy consumption and
cost of producing chemicals from both bulk and distributed feedstocks. This review article …

The design and operation issues for reactive distillation systems are considerably more
complex than those involved for either conventional reactors or conventional distillation …

This article first reviews recent developments in process synthesis and discusses some of
the major challenges in the theory and practice in this area. Next, the article reviews key …

This work presents a review of the main deterministic mixed‐integer nonlinear programming
(MINLP) solution methods for problems with convex and nonconvex functions. An overview …

The first guide to compile current research and frontline developments in the science of
process intensification (PI), Re-Engineering the Chemical Processing Plant illustrates the …

An approach is presented for determining an upper bound on the yield of a catalytic process,
which allows for variations in the catalytic chemistry. Scaling and thermodynamic arguments …

Process alternatives for continuous crystallization, ie, cascades of mixed suspension, mixed
product removal crystallizers (MSMPRCs) and plug flow crystallizers (PFCs), as well as …

This paper presents a review of advances that have taken place in the mathematical
programming approach to process design and synthesis. A review is first presented on the …

A strategy for synthesizing a reaction system to meet various business and technical
objectives is outlined. It replaces the conventional paradigm—the sequential evolution of the …

In this contribution, a methodology for the optimal design of chemical reactors based on the
best reaction route in the thermodynamic state space is proposed. This route is obtained by …