A short review on the intranasal delivery of diazepam for treating acute repetitive seizures

SHS Boddu, S Kumari - Pharmaceutics, 2020 - mdpi.com
Benzodiazepines such as diazepam, lorazepam and midazolam remained the mainstay of
treatment for acute repetitive seizures (ARS). The immediate care for ARS should often …

First-line management of canine status epilepticus at home and in hospital-opportunities and limitations of the various administration routes of benzodiazepines

M Charalambous, HA Volk, L Van Ham… - BMC veterinary …, 2021 - Springer
Status epilepticus (SE) or prolonged epileptic seizure activity is a common neurological
emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral …

[图书][B] Behavior problems of the dog and cat

G Landsberg, W Hunthausen, L Ackerman - 2012 - books.google.com
Formerly the Handbook of Behavior Problems of the Dog and Cat, the new edition of the
definitive guide to the diagnosis and treatment of behavior problems of the dog and cat has …

ACVIM Consensus Statement on the management of status epilepticus and cluster seizures in dogs and cats

M Charalambous, K Muñana… - Journal of veterinary …, 2024 - Wiley Online Library
Background Seizure emergencies (ie, status epilepticus [SE] and cluster seizures [CS]), are
common challenging disorders with complex pathophysiology, rapidly progressive drug …

A comparison of intranasal dexmedetomidine for sedation in children administered either by atomiser or by drops

BL Li, N Zhang, JX Huang, QQ Qiu, H Tian, J Ni… - …, 2016 - Wiley Online Library
Intranasal dexmedetomidine has been used successfully for sedation in children. A mucosal
atomisation device delivers an atomised solution to the nasal mucosa which facilitates rapid …

Intranasal midazolam versus rectal diazepam for the management of canine status epilepticus: a multicenter randomized parallel‐group clinical trial

M Charalambous, SFM Bhatti… - Journal of veterinary …, 2017 - Wiley Online Library
Background Intranasal administration of benzodiazepines has shown superiority over rectal
administration for terminating emergency epileptic seizures in human trials. No such clinical …

Pharmacokinetics of cannabidiol following intranasal, intrarectal, and oral administration in healthy dogs

D Polidoro, R Temmerman, M Devreese… - Frontiers in veterinary …, 2022 - frontiersin.org
The therapeutic potential of cannabidiol (CBD), a non-psychtropic component of the
Cannabis sativa plant, is substantiated more and more. We aimed to determine the …

Updates in the management of the small animal patient with neurologic trauma

J DiFazio, DJ Fletcher - Veterinary Clinics: Small Animal …, 2013 - vetsmall.theclinics.com
Neurologic trauma, encompassing traumatic brain injury (TBI) and acute spinal cord injury
(SCI), is a cause of significant morbidity and mortality in veterinary patients. In one recent …

Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs

L Vlerick, M Devreese, K Peremans, R Dockx… - PloS one, 2020 - journals.plos.org
Intranasal ketamine has recently gained interest in human medicine, not only for its sedative,
anaesthetic or analgesic properties, but also in the management of treatment resistant …

Out-of-hospital rescue medication in dogs with emergency seizure disorders: an owner perspective

C Kähn, SFM Bhatti, S Meller, N Meyerhoff… - Frontiers in veterinary …, 2023 - frontiersin.org
Background Emergency seizure disorders such as status epilepticus and cluster seizures
are unlikely to cease spontaneously while prolonged seizure activity become progressively …