The clinical management/understanding of brain metastases (BM) has changed
substantially in the last 5 years, with key advances and clinical trials highlighted in this …

Advances in chemotherapy and targeted therapies have improved survival in cancer
patients with an increase of the incidence of newly diagnosed brain metastases (BMs) …

BACKGROUND: Stereotactic radiosurgery (SRS) is an increasingly common modality used
with surgery for resectable brain metastases (BM). OBJECTIVE: To present a multi …

Leptomeningeal carcinomatosis (LC) is defined as infiltration of the leptomeninges by
metastatic carcinoma, a relatively uncommon but devastating complication of many …

METHODS Details of the systematic literature review are provided in the full text of this
guideline (https://www. cns. org/guidelines/guidelines-treatment-adults-metastatic-brain …

Purpose Preoperative radiosurgery (SRS) is a feasible alternative to postoperative SRS,
with potential benefits in adverse radiation effect (ARE) and leptomeningeal disease (LMD) …

Background Radiographic leptomeningeal disease (LMD) develops in up to 30% of patients
following postoperative stereotactic radiosurgery (SRS) for brain metastases. However, the …

Purpose Recent prospective data have shown that patients with solitary or oligometastatic
disease to the brain may be treated with upfront stereotactic radiosurgery (SRS) with deferral …

Importance Neurosurgical resection represents an important management strategy for
patients with large, symptomatic brain metastases and increasingly is followed by …

Pre-operative stereotactic radiosurgery (pre-SRS) has been shown as a viable treatment
option for resectable brain metastases (BM). The aim of this study is to compare oncologic …