Within living cells, mitochondria are considered relevant sources of reactive oxygen species
(ROS) and are exposed to reactive nitrogen species (RNS). During the last decade …

The rediscovery and reinterpretation of the Warburg effect in the year 2000 occulted for
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …

Mitochondrial dynamics is important for life. At center stage for mitochondrial dynamics, the
balance between mitochondrial fission and fusion is a set of dynamin‐related GTP ases that …

Mitochondrial fusion and structure depend on the dynamin-like GTPase OPA1, whose
activity is regulated by proteolytic processing. Constitutive OPA1 cleavage by YME1L and …

In the past mitochondria were considered as the “powerhouse” of cell, since they generate
more than 90% of ATP in aerobic conditions through the oxidative phosphorylation …

Mitochondria are dynamic organelles that continually undergo fusion and fission. These
opposing processes work in concert to maintain the shape, size, and number of …

Mitochondria are dynamic organelles that continually move, fuse and divide. The dynamic
balance of fusion and fission of mitochondria determines their morphology and allows their …

Apoptosis is a process of programmed cell death that serves as a major mechanism for the
precise regulation of cell numbers, and as a defense mechanism to remove unwanted and …

Mitochondrial fusion and fission events, collectively known as mitochondrial dynamics, act
as quality control mechanisms to ensure mitochondrial function and fine‐tune cellular …

Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …