The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Extrusion-based bioprinting (EBB) is a rapidly growing technology that has made substantial
progress during the last decade. It has great versatility in printing various biologics, including …

Since human embryonic stem cells were first differentiated to beating cardiomyocytes a
decade ago, interest in their potential applications has increased exponentially. This has …

Cells in their in vivo microenvironment constantly encounter and respond to a multitude of
signals. While the role of biochemical signals has long been appreciated, the importance of …

Proper tissue function and regeneration rely on robust spatial and temporal control of
biophysical and biochemical microenvironmental cues through mechanisms that remain …

Cell–material interactions constitute a key fundamental topic in biomaterials study. Various
cell cues and matrix cues as well as soluble factors regulate cell behaviors on materials …

Many types of mammalian cells can aggregate and differentiate into 3‐D multicellular
spheroids when cultured in suspension or a nonadhesive environment. Compared to …

Traditional methods of cell growth and manipulation on 2-dimensional (2D) surfaces have
been shown to be insufficient for new challenges of cell biology and biochemistry, as well as …

Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …

Developing biologically relevant models of human tissues and organs is an important
enabling step for disease modeling and drug discovery. Recent advances in tissue …