MJ Maroney, S Ciurli - Chemical reviews, 2014 - ACS Publications
The importance of nickel enzymes, where nickel serves as an essential cofactor, in Archaea, bacteria, plants, and primitive eukaryotes, is well documented. 1 Despite the fact that no …
Traces of metal are required for fundamental biochemical processes, such as photosynthesis and respiration. Cyanobacteria metal homeostasis acquires an important …
The glyoxalase system constitutes the major pathway for the detoxification of metabolically produced cytotoxin methylglyoxal (MG) into a non‐toxic metabolite d‐lactate. G lyoxalase I …
M Arai, N Nihonmatsu-Kikuchi, M Itokawa, N Rabbani… - 2014 - portlandpress.com
Glyoxalase I catalyses the isomerization of the hemithioacetal formed non-enzymatically from methylglyoxal and glutathione to Sd-lactoylglutathione. The activity of glyoxalase I is …
H Liu, S Yu, H Zhang, J Xu - 2012 - journals.plos.org
Diabetes impairs physiological angiogenesis by molecular mechanisms that are not fully understood. Methylglyoxal (MGO), a metabolite of glycolysis, is increased in patients with …
Background Glyoxalase pathway consists of two enzymes, glyoxalase I (GLYI) and glyoxalase II (GLYII) which detoxifies a highly cytotoxic metabolite methylglyoxal (MG) to its …
Nickel is an essential cofactor for some pathogen virulence factors. Due to its low availability in hosts, pathogens must efficiently transport the metal and then balance its ready …
Background The glyoxalase pathway is evolutionarily conserved and involved in the glutathione-dependent detoxification of methylglyoxal (MG), a cytotoxic by-product of …
The nickel metallome describes the distribution and speciation of nickel within the cells of organisms that utilize this element. This distribution is a consequence of nickel homeostasis …