Metal preferences and metallation

AW Foster, D Osman, NJ Robinson - Journal of biological chemistry, 2014 - ASBMB
The metal binding preferences of most metalloproteins do not match their metal
requirements. Thus, metallation of an estimated 30% of metalloenzymes is aided by metal …

Nonredox nickel enzymes

MJ Maroney, S Ciurli - Chemical reviews, 2014 - ACS Publications
The importance of nickel enzymes, where nickel serves as an essential cofactor, in Archaea,
bacteria, plants, and primitive eukaryotes, is well documented. 1 Despite the fact that no …

Metals in cyanobacteria: analysis of the copper, nickel, cobalt and arsenic homeostasis mechanisms

MJ Huertas, L López-Maury, J Giner-Lamia… - Life, 2014 - mdpi.com
Traces of metal are required for fundamental biochemical processes, such as
photosynthesis and respiration. Cyanobacteria metal homeostasis acquires an important …

A unique Ni2+ ‐dependent and methylglyoxal‐inducible rice glyoxalase I possesses a single active site and functions in abiotic stress response

A Mustafiz, A Ghosh, AK Tripathi, C Kaur… - The Plant …, 2014 - Wiley Online Library
The glyoxalase system constitutes the major pathway for the detoxification of metabolically
produced cytotoxin methylglyoxal (MG) into a non‐toxic metabolite d‐lactate. G lyoxalase I …

Measurement of glyoxalase activities

M Arai, N Nihonmatsu-Kikuchi, M Itokawa, N Rabbani… - 2014 - portlandpress.com
Glyoxalase I catalyses the isomerization of the hemithioacetal formed non-enzymatically
from methylglyoxal and glutathione to Sd-lactoylglutathione. The activity of glyoxalase I is …

Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor …

H Liu, S Yu, H Zhang, J Xu - 2012 - journals.plos.org
Diabetes impairs physiological angiogenesis by molecular mechanisms that are not fully
understood. Methylglyoxal (MGO), a metabolite of glycolysis, is increased in patients with …

Genome-wide analysis and expression profiling of glyoxalase gene families in soybean (Glycine max) indicate their development and abiotic stress specific response

A Ghosh, T Islam - BMC plant biology, 2016 - Springer
Background Glyoxalase pathway consists of two enzymes, glyoxalase I (GLYI) and
glyoxalase II (GLYII) which detoxifies a highly cytotoxic metabolite methylglyoxal (MG) to its …

Role of nickel in microbial pathogenesis

RJ Maier, SL Benoit - Inorganics, 2019 - mdpi.com
Nickel is an essential cofactor for some pathogen virulence factors. Due to its low availability
in hosts, pathogens must efficiently transport the metal and then balance its ready …

From methylglyoxal to pyruvate: a genome-wide study for the identification of glyoxalases and D-lactate dehydrogenases in Sorghum bicolor

B Bhowal, SL Singla-Pareek, SK Sopory, C Kaur - BMC genomics, 2020 - Springer
Background The glyoxalase pathway is evolutionarily conserved and involved in the
glutathione-dependent detoxification of methylglyoxal (MG), a cytotoxic by-product of …

Nickel metallomics: general themes guiding nickel homeostasis

AM Sydor, DB Zamble - Metallomics and the Cell, 2013 - Springer
The nickel metallome describes the distribution and speciation of nickel within the cells of
organisms that utilize this element. This distribution is a consequence of nickel homeostasis …