Anti-inflammatory and immunomodulatory effects of probiotics in gut inflammation: a door to the body

F Cristofori, VN Dargenio, C Dargenio… - Frontiers in …, 2021 - frontiersin.org
Hosting millions of microorganisms, the digestive tract is the primary and most important part
of bacterial colonization. On one side, in cases of opportunistic invasion, the abundant …

Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome

I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …

Scutellaria baicalensis Georgi polysaccharide ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function and modulating gut microbiota

L Cui, X Guan, W Ding, Y Luo, W Wang, W Bu… - International Journal of …, 2021 - Elsevier
The aim of this study was to investigate the effect of a polysaccharide from Scutellaria
baicalensis Georgi on UC. Gut microbiota dysbiosis is a worldwide problem associating with …

Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis

Y Lee, K Sugihara, MG Gillilland III, S Jon, N Kamada… - Nature materials, 2020 - nature.com
While conventional approaches for inflammatory bowel diseases mainly focus on
suppressing hyperactive immune responses, it remains unclear how to address disrupted …

Gut microbiota and intestinal trans-epithelial permeability

B Allam-Ndoul, S Castonguay-Paradis… - International journal of …, 2020 - mdpi.com
Constant remodeling of tight junctions to regulate trans-epithelial permeability is essential in
maintaining intestinal barrier functions and thus preventing diffusion of small molecules and …

Interaction between lipopolysaccharide and gut microbiota in inflammatory bowel diseases

M Candelli, L Franza, G Pignataro, V Ojetti… - International journal of …, 2021 - mdpi.com
Lipopolysaccharides (LPSs) are bacterial surface glycolipids, produced by Gram-negative
bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context …

Gut microbiota in the pathogenesis of inflammatory bowel disease

A Nishida, R Inoue, O Inatomi, S Bamba… - Clinical journal of …, 2018 - Springer
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a
chronic and relapsing inflammatory disorder of the intestine. Although its incidence is …

Probiotics in medicine: a long debate

E Stavropoulou, E Bezirtzoglou - Frontiers in immunology, 2020 - frontiersin.org
During the last years probiotics gained the attention of clinicians for their use in the
prevention and treatment of multiple diseases. Probiotics main mechanisms of action …

[PDF][PDF] Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 2: current management

M Harbord, R Eliakim, D Bettenworth… - Journal of Crohn's …, 2017 - academic.oup.com
11.1. General The treatment strategy for ulcerative colitis [UC] is mainly based on the
severity, distribution [proctitis, left-sided, extensive] 1 and pattern of disease. The latter …