Coumarin-containing hybrids and their anticancer activities

L Zhang, Z Xu - European Journal of Medicinal Chemistry, 2019 - Elsevier
Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

[HTML][HTML] Coumarin-heterocycle framework: A privileged approach in promising anticancer drug design

A Dorababu - European Journal of Medicinal Chemistry Reports, 2021 - Elsevier
The cancer cases are increasing in fast pace; most of them are resulted from exposure to
harmful pollutants. Genetic factors are responsible for cancer only to a small extent …

Recent advancements in the development of anti-breast cancer synthetic small molecules

EB Elkaeed, HAAE Salam, A Sabt, GH Al-Ansary… - Molecules, 2021 - mdpi.com
Among all cancer types, breast cancer (BC) still stands as one of the most serious diseases
responsible for a large number of cancer-associated deaths among women worldwide, and …

The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions

G Mohammadi Ziarani, R Moradi, T Ahmadi… - Molecular Diversity, 2019 - Springer
Hydroxycoumarins are some of the most versatile heterocyclic scaffolds and are frequently
applied in the synthesis of various organic compounds. 4-Hydroxycoumarin-based …

In situ decorated Mn–lysine complex on magnetic nanoparticles as a novel and reusable nanocatalyst in the synthesis of 4, 4′-(arylmethylene)-bis-(3-methyl-1 …

T Tamoradi, SM Mousavi, B Karmakar - Journal of the Iranian Chemical …, 2021 - Springer
In this work, we report a new and recoverable catalyst by anchoring the Mn–Lysine complex
on the surface of CoFe2O4 magnetic nanoparticles through a simple, rapid and eco-friendly …

Continuous Flow Intensification for the Synthesis of High-Purity Warfarin

DV Silva-Brenes, SK Reyes-Vargas… - … Process Research & …, 2023 - ACS Publications
While racemic warfarin was initially commercialized as a rodenticide, it has become the most
prescribed anticoagulant drug for prevention of blood clots and is part of the World Health …

Novel Areca Nut extract mediated preparation of TiO2 nanoparticles and its catalytic synthesis of 3, 3′-(phenyl methylene) bis-(4-hydroxy-2H-chromen-2-one) …

AK GC, YD Bodke, B Manjunatha, O Nagaraja - Chemical Data Collections, 2022 - Elsevier
The present study describes the preparation of Areca Nut extract mediated TiO 2 and its
catalytic application for the synthesis of 3, 3′-(phenyl methylene) bis-(4-hydroxy-2H …

Design and synthesis of bis-coumarinyl methanes from 4-hydroxy-coumarin and aldehydes catalysed by Amberlyst 15 via dual C–C coupling: introducing coumarin …

A Rudra Paul, S Sarkar, J Hossain, SA Hussain… - Research on Chemical …, 2022 - Springer
An efficient one pot synthesis of various bis-coumarinyl methane derivatives was
investigated by condensing a series of aldehydes with 4-hydroxy coumarin in the presence …

Synthetic methodologies to access bioactive bis-coumarin scaffold: a recent progress

P Bedi, D Chaudhary, R Bose, S Santra… - Zeitschrift für …, 2024 - degruyter.com
Heterocyclics particularly those containing oxygen and nitrogen atoms are unique
precursors for the synthesis of various agrochemicals and pharmaceuticals. Bis-coumarins …

Synthesis, antiproliferative activity and 2D-QSAR study of some 8-alkyl-2, 4-bisbenzylidene-3-nortropinones

RF George, N Samir, IM Ayoub… - Future Medicinal …, 2018 - Taylor & Francis
Aim: Colon cancer is the third leading cause of death worldwide; therefore, there is a need
for an effective therapy with lower side effects. Methods: A series of 8-alkyl-2, 4 …