The combination of transparency and accessible genetics is making zebrafish an
increasingly important model in studies of motor control. Much of the work on the model has …

Imaging and molecular approaches are perfectly suited to young, transparent zebrafish
(Danio rerio), where they have allowed novel functional studies of neural circuits and their …

The rhythmic firing behavior of spinal motoneurons is a function of their electrical properties
and synaptic inputs. However, the relative contribution of endogenous versus network …

Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity, affecting
millions of adolescents worldwide, but it lacks a defined theory of etiopathogenesis …

Children exposed to alcohol in utero have significantly delayed gross and fine motor skills,
as well as deficiencies in reflex development. The reasons that underlie the motor deficits …

shocked (sho) is a zebrafish mutation that causes motor deficits attributable to CNS defects
during the first2dof development. Mutant embryos display reduced spontaneous coiling of …

We have examined the localization and activity of the neural circuitry that generates
swimming behavior in developing zebrafish that were spinalized to isolate the spinal cord …

Glycine is a major inhibitory neurotransmitter in the spinal cord and brainstem. Recently, in
vivo analysis of glycinergic synaptic transmission has been pursued in zebrafish using …

General mechanisms of motor network development have often been examined in the spinal
cord because of its relative simplicity when compared to higher parts of the brain. Indeed …

The transparent spinal cord and electrically compact fast muscle of zebrafish offer the first
opportunity to perform simultaneous whole-cell patch-clamp recordings from both motor …