Neural plasticity, a fundamental mechanism of neuronal adaptation, is disrupted in
depression. The changes in neural plasticity induced by stress and other negative stimuli …

Depression is the leading cause of disability around the world, but little is known about its
pathology. Currently, the diagnosis of depression is made based on clinical manifestations …

Highlights•Diverse animal models of depression and anxiety have impaired neurogenesis.•
Neurogenesis is consistently boosted by antidepressants in animal models when animals …

Depression and dementia are major public health problems. Major depressive disorder
(MDD) and Alzheimer's disease (AD) reciprocally elevate the risk for one another. No …

Electroconvulsive therapy (ECT) is a time tested treatment modality for the management of
various psychiatric disorders. There have been a lot of modifications in the techniques of …

Importance Electroconvulsive therapy (ECT) is one of the most effective treatments for
severe depression. However, biomarkers that accurately predict a response to ECT remain …

Background Electroconvulsive therapy (ECT) elicits a rapid and robust clinical response in
patients with refractory depression. Neuroimaging measurements of structural plasticity …

The rate of age-associated cognitive decline varies considerably between individuals. It is
important, both on a societal and individual level, to investigate factors that underlie these …

Background Hippocampal enlargements are commonly reported after electroconvulsive
therapy (ECT). To clarify mechanisms, we examined if ECT-induced hippocampal volume …

Previous animal models and structural imaging investigations have linked hippocampal
neuroplasticity to electroconvulsive therapy (ECT) response, but the relationship between …