The burden of tuberculosis (TB) in children and adolescents remains very significant.
Several million children and adolescents are infected with TB each year worldwide following …

Background: Interferon-gamma release assays (IGRA) are well-established
immunodiagnostic tests for tuberculosis (TB) in adults. In children these tests are associated …

Tuberculosis (TB) remains an important problem among children in the United States and
throughout the world. There is no diagnostic reference standard for latent tuberculosis …

Tuberculosis (TB) is one of the leading causes of childhood morbidity and death globally.
Lack of rapid, effective non-sputum diagnosis and prediction methods for TB in children are …

BACKGROUND: New guidelines support using interferon-γ release assays (IGRAs) in
children≥ 2 years for diagnosis of latent tuberculosis infection (LTBI). However, lack of …

Summary The World Health Organization aims to end the TB epidemic by 2035 whereas the
United Nations' Sustainable Developmental Goals sets this ambitious target for 2030 …

Background: Vitamin D has an immuomodulatory role in vaccine response and this may be
mediated via its action on antigen presenting cells with the most potent effects on dendritic …

Results PTB was more common in older females. Extrapulmonary manifestations and hilar
lymphadenopathy were more frequent in younger age. Both positive tuberculin skin test and …

Background: In Egypt, tuberculosis (TB) is considered the third most important public health
problem after schistosomiasis and hepatitis C. We sought to investigate the immune …

Background Tuberculin skin test (TST) is a delayed hypersensitivity reaction of latent TB
infected patients and BCG vaccinated individuals. It is recommended for screening of …