[HTML][HTML] Conscious processing and the global neuronal workspace hypothesis

GA Mashour, P Roelfsema, JP Changeux, S Dehaene - Neuron, 2020 - cell.com
We review the central tenets and neuroanatomical basis of the global neuronal workspace
(GNW) hypothesis, which attempts to account for the main scientific observations regarding …

Thalamic subnetworks as units of function

DS Roy, Y Zhang, MM Halassa, G Feng - Nature neuroscience, 2022 - nature.com
The thalamus engages in various functions including sensory processing, attention, decision
making and memory. Classically, this diversity of function has been attributed to the nuclear …

Maintenance of persistent activity in a frontal thalamocortical loop

ZV Guo, HK Inagaki, K Daie, S Druckmann, CR Gerfen… - Nature, 2017 - nature.com
Persistent neural activity maintains information that connects past and future events. Models
of persistent activity often invoke reverberations within local cortical circuits, but long-range …

Thalamic projections sustain prefrontal activity during working memory maintenance

SS Bolkan, JM Stujenske, S Parnaudeau… - Nature …, 2017 - nature.com
The mediodorsal thalamus (MD) shares reciprocal connectivity with the prefrontal cortex
(PFC), and decreased MD–PFC connectivity is observed in schizophrenia patients. Patients …

Korsakoff's syndrome: a critical review

NJM Arts, SJW Walvoort… - … disease and treatment, 2017 - Taylor & Francis
In this review, we present a survey on Korsakoff's syndrome (KS), a residual syndrome in
patients who suffered from a Wernicke encephalopathy (WE) that is predominantly …

Targeting thalamic circuits rescues motor and mood deficits in PD mice

Y Zhang, DS Roy, Y Zhu, Y Chen, T Aida, Y Hou… - Nature, 2022 - nature.com
Although bradykinesia, tremor and rigidity are the hallmark motor defects in patients with
Parkinson's disease (PD), patients also experience motor learning impairments and non …

The nucleus reuniens of the thalamus sits at the nexus of a hippocampus and medial prefrontal cortex circuit enabling memory and behavior

MJ Dolleman-van der Weel, AL Griffin, HT Ito… - Learning & …, 2019 - learnmem.cshlp.org
The nucleus reuniens of the thalamus (RE) is a key component of an extensive network of
hippocampal and cortical structures and is a fundamental substrate for cognition. A common …

The mediodorsal thalamus: an essential partner of the prefrontal cortex for cognition

S Parnaudeau, SS Bolkan, C Kellendonk - Biological psychiatry, 2018 - Elsevier
Deficits in cognition are a core feature of many psychiatric conditions, including
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …

Reciprocal circuits linking the prefrontal cortex with dorsal and ventral thalamic nuclei

DP Collins, PG Anastasiades, JJ Marlin, AG Carter - Neuron, 2018 - cell.com
Reciprocal interactions between the prefrontal cortex (PFC) and thalamus play a critical role
in cognition, but the underlying circuits remain poorly understood. Here we use optogenetics …

The impact of NMDA receptor hypofunction on GABAergic neurons in the pathophysiology of schizophrenia

SM Cohen, RW Tsien, DC Goff, MM Halassa - Schizophrenia research, 2015 - Elsevier
While the dopamine hypothesis has dominated schizophrenia research for several decades,
more recent studies have highlighted the role of fast synaptic transmitters and their receptors …