Wall teichoic acids of gram-positive bacteria

S Brown, JP Santa Maria Jr… - Annual review of …, 2013 - annualreviews.org
The peptidoglycan layers of many gram-positive bacteria are densely functionalized with
anionic glycopolymers known as wall teichoic acids (WTAs). These polymers play crucial …

Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions

C Weidenmaier, A Peschel - Nature Reviews Microbiology, 2008 - nature.com
Abstract Abstract| Most Gram-positive bacteria incorporate membrane-or peptidoglycan-
attached carbohydrate-based polymers into their cell envelopes. Such cell-wall …

Bacterial cell wall synthesis: new insights from localization studies

DJ Scheffers, MG Pinho - Microbiology and molecular biology …, 2005 - Am Soc Microbiol
In order to maintain shape and withstand intracellular pressure, most bacteria are
surrounded by a cell wall that consists mainly of the cross-linked polymer peptidoglycan …

The wall teichoic acid and lipoteichoic acid polymers of Staphylococcus aureus

G Xia, T Kohler, A Peschel - International Journal of Medical Microbiology, 2010 - Elsevier
Staphylococci and most other Gram-positive bacteria incorporate complex teichoic acid (TA)
polymers into their cell envelopes. Several crucial roles in Staphylococcus aureus fitness …

Wall Teichoic Acid Polymers Are Dispensable for Cell Viability in Bacillus subtilis

MA D'Elia, KE Millar, TJ Beveridge… - Journal of …, 2006 - Am Soc Microbiol
An extensive literature has established that the synthesis of wall teichoic acid in Bacillus
subtilis is essential for cell viability. Paradoxically, we have recently shown that wall teichoic …

Lesions in Teichoic Acid Biosynthesis in Staphylococcus aureus Lead to a Lethal Gain of Function in the Otherwise Dispensable Pathway

MA D'Elia, MP Pereira, YS Chung, W Zhao… - Journal of …, 2006 - Am Soc Microbiol
An extensive study of teichoic acid biosynthesis in the model organism Bacillus subtilis has
established teichoic acid polymers as essential components of the gram-positive cell wall …

Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics

EWC Sewell, ED Brown - The Journal of antibiotics, 2014 - nature.com
Wall teichoic acids are a major and integral component of the Gram-positive cell wall. These
structures are present across all species of Gram-positive bacteria and constitute roughly …

Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM

G Xia, L Maier, P Sanchez-Carballo, M Li, M Otto… - Journal of Biological …, 2010 - ASBMB
Wall teichoic acid (WTA) glycopolymers are major constituents of cell envelopes in
Staphylococcus aureus and related Gram-positive bacteria with important roles in cell wall …

A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps

S Brown, YH Zhang, S Walker - Chemistry & biology, 2008 - cell.com
Resistance to every family of clinically used antibiotics has emerged, and there is a pressing
need to explore unique antibacterial targets. Wall teichoic acids (WTAs) are anionic …

Cell wall assembly in Bacillus subtilis: how spirals and spaces challenge paradigms

AP Bhavsar, ED Brown - Molecular microbiology, 2006 - Wiley Online Library
Although the bacterial cell wall has been the subject of decades of investigation, recent
studies continue to generate novel and controversial models of its synthesis and assembly …